Rhinosinusitis is increasing in prevalence and incidence, and has been estimated to affect approximately 31 million patients in the United States each year. This comprehensive reference offers recommendations for the optimal treatment of chronic rhinosinusitis and indicates pathways for new research in the field. Offering an interdisciplinary approach to the topic, edited by an allergist and an otolaryngologist, this source discusses advances in the understanding of the pathophysiology of the diseases, as well as important diagnostic tools for the assessment of chronic rhinosinusitis. It also summarizes published studies of chronic rhinosinusitis management for evidence-based medical care.
Clinical Patterns of Illness and Disease Classification. Impact of CRS on QOL and Medical Expenditure. Environmental and Allergic Factors; Experimental Models. Innate & Acquired Immunity and Epithelial Cell Function. Role of T Cells and Eosinophils in CRS. Role of Mast Cells and Basophils in CRS. Mucociliary Transport in CRS. Glandular and Vascular Abnormalities in CRS. Bacterial Infection and Antibiotic Treatment in CRS. Bacteria as Immune Stimulant in CRS. Fungi as Immune Stimulant EFRS. Radiologic Assessment of CRS Including Image Guided Technology. Role of Rhinoscopic Assessment in Medical Management. Role of Steroids in Treatment of RS +/- Polyposis. Ancillary Therapies in CRS. Classic AFS Including Clinical Trials. Medical Management of RS Comorbidities. Special Considerations Regarding Pediatric CRS. Approach to Evaluation and Medical Management of CRS. Interfacing Medical Surgical Management of CRS