Best Seller!
Cilia and Mucus: From Development to Respiratory Defense, 1st Edition (Hardback) book cover

Cilia and Mucus

From Development to Respiratory Defense, 1st Edition

By Matthias Salathe

CRC Press

456 pages

Purchasing Options:$ = USD
Hardback: 9780824704414
pub: 2001-07-27
SAVE ~$64.00
$320.00
$256.00
x


FREE Standard Shipping!

Description

This book details advances in research regarding cilia, mucus, and mucociliary clearance, examining changes in mucus expression and goblet cell metaplasia, and assessing the ability of the mucociliary system to respond to abnormalities.

Recognizes that cilia and dynein arms play pivotal roles in developing mammalian embryos!

Examines the role of genetics in normal and abnormal ciliary function!

Discussing scientific fundamentals, current diagnostic techniques, and clinically tested treatments, Cilia and Mucus

  • analyzes the regulation of ciliary waves at the cellular level

  • considers irregularities of upper and lower airways and cilia in systems of the body

  • explores potential modulators of airway mucin secretion

  • proposes a novel therapy for airway hypersecretion due to the epidermal growth factor cascade

  • clarifies gamma camera imaging to measure mucociliary clearance

  • describes the effect of purinergic receptors and dry powder mannitol on airway passages

  • and more!

    With contributions from over 100 international researchers and clinicians, and containing over 1300 references, drawings, photographs, tables, and equations, Cilia and Mucus is a unique single-source reference for pulmonologists, physiologists, immunologists, allergists, otolaryngologists, pediatricians, microbiologists, basic scientists, and graduate and medical school students in these disciplines.

  • Reviews

    "

    …a comprehensive and up-to-date review of the topic.

    "-Allergy

    Table of Contents

    CILIA

    Cytoplasmic Dynein-2 and Ciliogenesis

    David J. Asai

    Dynein Motor Activity During Ciliary Beating

    Michael E. J. Holwill

    Ciliary Growth by Intraciliary Trafficking

    Dawn Signor, Karen P. Wedaman, Jose T. Orozco, Lesilee S. Rose, and Jonathan M. Scholey

    The Regulation of Airway Ciliary Beat Frequency by Intracellular Calcium

    Michael J. Sanderson, Alison B. Lansley, and John H. Evans

    Modeling the Response of Mammalian Ciliary Beating to Changes in Cytoplasmic Calcium

    Matthias Salathe and Richard J. Bookman

    Enhancement of CBF Is Dominantly Controlled by PKG and/or PKA

    Alex Braiman, Natalya Uzlaner, and Zvi Priel

    Modulation of Ciliary Motility by Na+

    Shai D. Silberberg, Alon Korngreen, Weiyuan Ma, Natalya Uzlaner, and Zvi Priel

    Presentation of Ciliary Beat Frequency Results to Our Peers

    X. Mwimbi, R. Muimo, and Anil Mehta

    Identifying the Genes for Primary Ciliary Dyskinesia and Kartagener Syndrome

    Michal Witt, Ewa Rutkiewicz, Yue-Fen Wang, Cui-e Sun, Diego F. Wyszynski, Scott R. Diehl, Jacek Pawlik, and Jerzy Zebrak

    Homozygosity Mapping as an Approach for Identifying Genes Involved in Primary

    Ciliary Dyskinesia S. L. Spiden and H. M. Mitchison

    Mutations in the Novel Mammalian Gene DNAI1 Result in Primary Ciliary Dyskinesia

    Gaëlle Pennarun, Catherine Chapelin, Anne-Marie Bridoux, Valère Cacheux, Michel Goossens, Serge Amselem, Bénédicte Duriez, Estelle Escudier, Gilles Roger, and Annick Clément

    Molecular Strategies for the Study of Human Cilia

    Lawrence E. Ostrowski

    Ciliated Ependymal Cells: The Effect of Streptococcus pneumoniae on the Beat Frequency Response

    Robert A. Hirst, T. J. Mitchell, P. W. Andrew, and C. O'Callaghan

    The Cytoprotective Effects of Macrolides, Azalides, and Ketolides on Human Ciliated Epithelium In Vitro

    Charles Feldman, Ronald Anderson, Annette J. Theron, Peter Cole,and Robert Wilson

    Examining Mucociliary Differentiation of Human Nasal Epithelial Cells In Vitro

    J. Laoukili, K. Million, O. Houcine, F. Marano, Frédéric Tournier, E. Perret, and D. Caput

    MUCUS

    Respiratory Tract Mucins

    Julia R. Davies and Ingemar Carlstedt

    MARCKS Protein: A Potential Modulator of Airway Mucin Secretion

    Yuehua Li, Linda D. Martin, and Kenneth B. Adler

    Airway Goblet and Mucous Cells: Identical, Similar, or Different?

    C. William Davis and Scott H. Randell

    Regulation of Respiratory Mucin Gene Expression by Neutrophil Elastase

    Judith A. Voynow and Bernard M. Fischer

    Pseudomonas Adhesion to MUC1 Mucins: A Potential Role of MUC1 Mucins in Clearance of Inhaled Bacteria

    Kwang Chul Kim, Sang Won Hyun, Beom Tae Kim, Daoud Meerzaman, Min Ki Lee, and ErikLillehoj

    High-Density DNA Microarray Membranes to Study Gene Expression Patterns Associated with Human Airway Epithelial Cell Differentiation in Culture

    Mary M. J. Chang, Yin Chen, Yu Hua Zhao, Reen Wu, Ching Li, and Konan Peck

    In Vivo Models of Airway Goblet Cell Hyperplasia and Mucin Gene Expression

    Alinka K. Smith and Duncan F. Rogers

    Interleukin-13-Induced Mucous Cell Hyperplasia in Airway Epithelium

    Linda D. Martin, Brian W. Booth, Nancy J. Akley, Kenneth B. Adler, Mariangela Macchione, and James C. Bonner

    Airway Mucins and Lung Cancer

    Chong-Jen Yu and Pan-Chyr Yang

    Charged Oligosaccharides as Novel Mucolytic Therapies

    Malcolm King, Eiichi Sudo, and Martin M. Lee

    MUCOCILIARY INTERACTIONS

    Modeling Aspects of Tracer Transport in Mucociliary Flows

    J. R. Blake and E. A. Gaffney

    P2Y2 Receptors and Ca2+-Dependent Cl- Secretion in Normal and Cystic Fibrosis Human Airway Epithelia

    Carla M. Pedrosa Ribeiro, Anthony M. Paradiso, Eduardo Lazarowski, and Richard C. Boucher

    Role of Epidermal Growth Factor Receptor Cascade in Airway Hypersecretion and Proposal for Novel Therapy

    Jay A. Nadel

    In Vivo Measurement of Mucociliary Clearance: The Use of Gamma Camera Imaging

    Joy Conway

    Regulation of Mucociliary Clearance by Purinergic Receptors

    William D. Bennett, Peadar G. Noone, Michael Knowles, and Richard C. Boucher

    The Effect of Dry Powder Mannitol on the Clearance of Mucus

    Evangelia Daviskas, Michael Robinson, Sandra D. Anderson, and Peter T. P. Bye

    Neutrophil Elastase and Antigen-Induced Mucociliary Dysfunction

    Thomas O'Riordan and William M. Abraham

    Mechanisms of Clearance of Soluble Substances from the Intrathoracic Airways

    W. Michael Foster and Elizabeth M. Wagner

    The Role of Cough in Lung Mucus Clearance

    Amir Hasani and John E. Agnew

    Cough Clearance of Mucus Simulants in Endotracheal Tubes: Patterns of Catastrophic Separation at Controlled Linear Velocities

    Peter Krumpe, Bruce Denney, Amgad Hassan,Ross Albright, and Cahit Evrensel

    Subject Categories

    BISAC Subject Codes/Headings:
    MED079000
    MEDICAL / Pulmonary & Thoracic Medicine
    SCI017000
    SCIENCE / Life Sciences / Cytology