Clin-Alert 2001: A Quick Reference to Adverse Clinical Events, 1st Edition (Hardback) book cover

Clin-Alert 2001

A Quick Reference to Adverse Clinical Events, 1st Edition

By Joyce Generali

CRC Press

270 pages

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Hardback: 9781587160783
pub: 2001-02-05
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Now the adverse drug reaction events reported in the newsletter Clin-Alert during Y2000 have been compiled, organized, re-formatted, indexed, and published in a convenient one-volume reference book, Clin-Alert 2001.

The new book contains the full texts of all 311 reports from Clin-Alert newsletter 2000 issues. The reports have been grouped by fourteen major drug categories and indexed in six different ways for quick look-up.

The reports were originally prepared for the Clin-Alert newsletter based on an ongoing search of more than 100 major medical journals, and summarization of key information included in journal articles on adverse drug reaction events. The summary reports were prepared by drug information specialists, and include the following information:

o generic name of the drug or other substance involved

o a brief characterization of the adverse reaction

o a one paragraph summary of the event and related patient information

o the author's conclusions or warnings

o original source information

Established in 1962, the Clin-Alert newsletter is a semi-monthly drug information service widely used by healthcare professionals involved in drug therapy and administration. It is independent, accepts no advertising, and is published for professional use. Now published, Clin-Alert 2001 provides an easy-to-use, quick and reliable reference that will be useful to healthcare professionals working with drugs.

Table of Contents

Chapter headings and small samplings of report titles

Each chapter on a drug group begins with an index in table format of the drugs and related ADRs reported in the chapter.


Alternative Medicines

o Androstendedione: Priapism o Aristolochic Acid: Nephrotoxicity, FDA Advisory o Averrhoa Carambola (Star Fruit): Death in Uremic Patients o Chromium Picolinate: Exanthematous Pustulosis (First Report)


o General Antibiotics: Rash in Pediatric Patients o Aminoglycosides Gentamicin: Excessive Dosage: Neurotoxicity and Otototoxicity, Legal Action o Antifungals/Fluconazole: Fixed Drug Eruption o Fluconazole: QT Prolongation, Torsades de Pointes


o Antineoplastic Chemotherapy: Decreased Cognitive Function in Breast Cancer Patients o Chlorambucil: Acute Hepatic Failure (First Report) o Cyclophosphamide (High Dose): Congestive Heart Failure (QT Dispersion as Predictor)


o Abciximab with Clopidogrel or Ticlopidine: Incidence of Thrombocytopenia o Abciximab: Thrombocytopenia o Alteplase: Anaphylactoid Reactions, Angioedema


o Amiodarone: Hyponatremia (Second Report) o Amiodarone: Pulmonary Toxicity o Amiodarone: Lupus


o Analgesics-Nsaids Acetaminophen: Anaphylactoid Reaction o Celecoxib: Hypoprothrombinemia, Gastropathy o Celecoxib: Auditory Hallucinations


o Beta-Blockers (Ocular): Incidence of Ocular Side Effects o Brimonidine: Psychosis (First Report) o Dextromethorphan and Pseudoephedrine: Psychosis o Dextromethorphan: Psychosis

Gastrointestinal Agents

o Alosetron: FDA Advisory: Ischemic Colitis, Constipation o Calcium Carbonate: Milk Alkali Syndrome o Calcium Carbonate and Levothyroxine: Interaction: T4 Absorption Reduced


o Diabetic Agents/Glimepiride: Thrombocytopenic Purpura (First Report) o Glyburide and Ciprofloxacin: Interaction: Resistant Hypoglycemia o Metformin: Hemolytic Anemia (Second Report)


o Megavitamins/Minerals: Fatal Hypermagnesemia


o General: Adverse Drug Event (ADEs) Risk Factors in Hospitalized Patients o Adverse Drug Reactions: Hospital Admissions o Hepatic Adverse Drug Reactions: Inaccurate Reporting o Intravenous Extrvasation: Hand Disfiguration

Respiratory Agents

o Beclomethasone, Fluticasone (Inhaled): Growth Velocity Reduction o Beta-Agonists (Inhaled): Myocardial Infarction Risk o Fluticasone (Inhaled): Invasive Pulmonary Aspergillosis (First Report) o Ipratropium Bromide (Inhaled): Blurred Vision


o Benzocaine: Methemoglobinemia o Benzocaine/Tetracaine/Butyl Aminobenzoate: Methemoglobinemia o Camphor (Topical): Hepatotoxicity (First Report)


o Anthrax Vaccine: Adverse Events o Antithymocyte Globulin: Acute Renal Failure (First Report) o Bacillus Calmette Guerin Vaccine: Systemic Granulomatous Disease


Drug Interaction Index (drug, interacting drug and ADR)

FDA/Manufacturer Alert Index

Legal Action Index

Newly Marketed Drugs: 1997-2000

Drug Index

Subject Categories

BISAC Subject Codes/Headings:
MEDICAL / Pharmacy