Clinical Andrology A Practical Handbook

About the Editors

List of Contributors

Preface

1 Embryology of the Male Reproductive System

Mark Yao, Majed Shabbir and Maria Satchi

2 Anatomy and Physiology of the Male Reproductive System

Adam Jones, Christina Fontaine, Odunayo Kalejaiye and Vaibhav Modgil

3 Aetiology, Pathophysiology and Clinical Assessment of Erectile Dysfunction

Ian Eardley

4 The Management of Erectile Dysfunction

Ali Alrawahneh, Karl H. Pang and Hussain M. Alnajjar

5 Aetiology, Pathophysiology, Clinical Assessment and Management of Ejaculatory Disorders

Muslim Dogan Deger and Ege Can Serefoglu

6 Peyronie’s Disease: Aetiology, Pathophysiology and Clinical Assessment

Neil James Harvey, Xenia Sara and Ian Pearce

7 Management of Penile Deformity

Niall Kelly and Rowland Rees

8 Male Sterilisation: Clinical Assessment and Surgical Technique

Kirby F. Sebro, Karen Randhawa and C.J. Shukla

9 Vasectomy Reversal

Matthew J. Rewhorn and David J. Ralph

10 Aetiology and Pathophysiology of Obstructive and Non-Obstructive Causes of Male Factor Infertility

Amr Elmekresh, Rozh Jalil, Selcuk Guven and Kamran Ahmed

11 Clinical Assessment of Male Factor Infertility

Chloe Mount and Philippa Sangster

12 Management of Male Factor Infertility

Ankit Desai and Suks Minhas

13 Aetiology, Pathophysiology, Clinical Assessment, and Management of Primary Hypogonadism

Nipun Lakshitha de Silva, Jas Kalsi and Channa N. Jayasena

14 Urethral Stricture

Hermione Tsoi Hannah Pendegast and Nadir I. Osman

15 Aetiology, Pathophysiology and Clinical Assessment and Management of Penile Cancer

Sachin Yallapa, Karl H. Pang, Asif Muneer and Hussain M. Alnajjar

16 Aetiology, Pathophysiology, Clinical Assessment and Management of Testis Cancer

Muhammad Haider, Pinky Kotecha, Nasreen Aziz, Prabhakar Rajan, Walter Cazzaniga and David Nicol

17 Aetiology, Pathophysiology and Clinical Assessment and Management of Priapism

Jamie Lindsay, Stanley Tang, Karl H. Pang and Asif Muneer

18 Aetiology, Pathophysiology and Clinical Assessment and Management of Fournier’s Gangrene

Matthew H.V. Byrne, Paul Hadway and Shafi Wardak

19 Aetiology, Pathophysiology and Clinical Assessment and Management of Genito-Urethral Trauma

Luca Ongaro, Francesco Claps, Carlo Trombetta, Giovanni Ligu

Biography

Karl H. Pang MBChB, BSc (Hons), MSc, PhD, AFHEA, FRCS (Urol), FEBU

Karl Pang is a Consultant Urological Surgeon and Andrologist (locum) at Chelsea and Westminster Hospital NHS Foundation Trust, and an Honorary Associate Professor at University College London. He underwent specialist training in the Yorkshire and Humber Deanery and received fellowship training in andrological surgery at University College London Hospital. He was Clinical Assistant Professor within the Department of Surgery, University of Hong Kong and Queen Mary Hospital between 2023 and 2024. He obtained his intercalated BSc in Immunobiology from King’s College London, and his MSc in Medical Research and PhD in Cancer Epigenetics from the University of Sheffield. He received funding from the Urology Foundation and the Royal College of Surgeons of England for his PhD and ongoing research.

He was the chief editor of Basic Urological Science (CRC Press) and Challenging Cases in Urological Surgery (Oxford Press). The former book received an annual BMA book award. He previously served in both the EAU-YAU Men’s Sexual and Reproductive Health Group and the Penile and Testis Cancer Group, and is currently a senior associate of the EAU Guidelines Office and a member of the ISSM Young Researchers Committee. His clinical and research interests are in men’s sexual and reproductive health and male genital cancer.

Asif Muneer MBChB, MD, PhD, FRCS (Urol)

Asif Muneer is Professor of Urology and Surgical Andrology at University College London. He is a Consultant Urological Surgeon and Andrologist based at University College London Hospital. Having completed his research degree (MD) at UCL, he went on to complete his higher surgical training in Oxford. He has also completed a PhD and published widely on all aspects of urology, with his main interest being andrology and male genital cancers. He has edited several books including Textbook of Penile Cancer, Atlas of Male Genitourethral Surgery and Prosthetic Surgery in Urology. He has lectured and delivered training courses both nationally and internationally and is the Past President of the British Society for Sexual Medicine and past Chair of the BAUS Section of Andrology. He is also past honorary Secretary of BAUS.

He has received a number of awards including the Keith Yeates Gold Medal for the intercollegiate FRCS and the Harold Hopkins Golden Telescope award from the British Association of Urological Surgeons.

Hussain M. Alnajjar BSc (Medical Sciences), BSc (Medical Sciences), MBBS, ChM (Urol), FEBU, FRCS (Urol)

Mr Hussain M. Alnajjar is a Consultant Urological and Andrological Surgeon at University College London Hospitals (UCLH) and an Honorary Associate Professor at University College London (UCL).

He leads a high-volume, specialised andrology practice with a national quaternary referral base for complex cases. His clinical expertise includes the advanced surgical management of Peyronie’s disease, penile prosthesis implantation, male infertility, penile and testicular cancer, and male genital reconstruction. His practice is defined by excellence in care, innovation in technique, and a commitment to outcomes-driven surgery.

Mr Alnajjar has received numerous prestigious awards in recognition of his outstanding clinical and academic achievements. He is widely published in leading peer-reviewed journals and has authored and co-edited several influential textbooks and book chapters in the field of andrology. He remains actively involved in clinical research and academia and is a regular national and international speaker.

He was recently elected Secretary of the Andrology Executive Committee of the British Association of Urological Surgeons (BAUS). A dedicated educator and mentor, he trains senior andrology fellows and acts as a proctor for penile prosthesis implantation and complex andrological surgeries. He is an examiner for the Membership of the Royal College of Surgeons of England (MRCS) and has previously served on the European Board of Urology Examination Committee, as well as the scientific committees of the European Society for Sexual Medicine (ESSM) and the Middle East Society for Sexual Medicine (MESSM).