2nd Edition

Clinical Asthma Theory and Practice

Edited By Jonathan A. Bernstein, Mark L. Levy Copyright 2026
312 Pages 49 B/W Illustrations
by CRC Press

312 Pages 49 B/W Illustrations
by CRC Press

Enormous progress in asthma research has been made in the past 50 years, including a greater understanding of its complex pathogenesis and new and more effective therapies. Consequently, the scientific literature has grown vast and can be difficult to integrate. With contributions from a distinguished panel of world-renowned authors, the Second Edition of Clinical Asthma: Theory and Practice... Read more

SECTION I. The Basics of Asthma

Chapter 1. Understanding Asthma: A Global Epidemiological Perspective

Syed Ahmar Shah, Aziz Sheikh, and Colin Simpson

Chapter 2. Immunopathogenesis

Chris J. Corrigan

Chapter 3. Smartinhalers, Telemedicine and Artificial Intelligence, and the Future of Asthma Care Worldwide

Job F.M. van Boven, Chi Yan Hui, and Hilary Pinnock

Chapter 4. Endotypes and Asthma

Sarah Diver, Richard Russell, and Pranabashis Haldar

SECTION II. Diagnosis of Asthma

Chapter 5. Guidelines in Asthma

Krystelle Godbout and Louis-Philippe Boulet

Chapter 6. Diagnosis of Asthma in Preschool Children

Liesbeth Duijts and Tarik Karramass

Chapter 7. Diagnosis of Asthma in Older Children and Adults

Anchalee Senavonge and Paul M O’Byrne

Chapter 8. United Airways: Managing Patients with Allergic Rhinitis and Asthma

Glenis K. Scadding and Guy Scadding

SECTION III. Asthma Triggers

Chapter 9. Viral Infections in Asthma

René Lutterand Bart Hilvering

Chapter 10. Asthma and Allergens

Anna Zhang, Sachin Baxi, and Wanda Phipatanakul

Chapter 11. Air Pollutants

Meghan E. Rebuli, Chris Carlsten, and Neil E Alexis

Chapter 12. Exercise-Induced Bronchoconstriction

Justin Greiwe, Anil Nanda, and Sharmilee M. Nyenhuis

SECTION IV. Asthma Education and Outcomes

Chapter 13. Asthma Education

Vanessa M. McDonald, Kirsten R. Murray, and Peter G. Gibson

Chapter 14. Adherence and Outcomes

Andrew Bush

Chapter 15. Inhaler Devices

Federico Lavorini, Alessandra Sorano, and Mark L. Levy

SECTION V. Asthma Management and Treatments

Chapter 16. Management of Pediatric Asthma

Jeffrey R Stokes and Leonard B. Bacharier

Chapter 17. Management of Adolescent Asthma

Laura Chen, Beverley J. Sheares, and Jean-Marie Bruzzese

Chapter 18. Management of Adult Asthma

S Shahzad Mustafa, Sara Patrawala, and Thomas B. Casale

Chapter 19. Management of Asthma in Older Adults

Tolly E.G. Epstein, Alan P. Baptist, Anil Nanda, Andrew M. Smith, Deborah Lee, and Jenny J. Lee

Chapter 20. Severe Acute and Life-Threatening Asthma in Children

Adam Lawton, Andrew Nyman, and Louise Fleming

Chapter 21. Severe Acute and Chronic Life-Threatening Asthma in Adults

Engi Ahmed, Jérémy Charriot, Isabelle Vachier, Laureen Hurault, Clément Boissin, and Arnaud Bourdin

Chapter 22. Learning from Asthma Deaths to Prevent Attacks

Mark L. Levy

SECTION VI. Asthma and Special Populations

Chapter 23. Occupational Asthma

Joshua S. Bernstein and Jonathan A. Bernstein

Chapter 24. Pregnancy and Asthma

Arzu Yorgancioglu

Chapter 25. Anxiety and Depression and Asthma

Alison C. McLeish

SECTION VII. Approach to Asthma Worldwide and in the Primary Care Setting

Chapter 26. Managing Asthma and Allergy: The need for a Countrywide Approach to Integrating Care

Luane Marques de Mello and Álvaro Augusto Cruz

Chapter 27. Primary Care Setting and Integrating Care across Primary/Secondary Care Interface

Alan G. Kaplan and Barbara P. Yawn

Biography

Jonathan A. Bernstein, MD, is Professor of Clinical Medicine in the Department of Internal Medicine, Division of Rheumatology, Allergy and Immunology at the University of Cincinnati Medical Center and a partner of Advanced Allergy Services and Bernstein Clinical Research Center. He received his MD from the University of Cincinnati College of Medicine (1981–1985), completed his residency in Internal Medicine at the Cleveland Clinic Hospital (1985–1988) and Allergy/Clinical Immunology training at Northwestern University (1988–1990). He has been a faculty member of UC since 1990. He is the immediate past president of the AAAAI (2022–2023). He is also a member of the Joint Task Force Guideline committee, the WAO board of directors, President of Interasma, GINA advocacy council, HAEA organization medical advisory board, and WE CU patient advocacy organization. He is a member of the Cincinnati Alpha Lambda Omega society. Dr. Bernstein is a DIA-certified clinical trial investigator and conducting multicenter and physician-initiated clinical therapeutic trials for a number of clinical conditions including asthma, chronic urticaria, hereditary angioedema, atopic dermatitis, and systemic mastocytosis and is considered a key opinion leader in these areas. He was the editor-in-chief of the Journal of Asthma from 2009 to 2022 and is currently on the editorial board for the Journal of Allergy Clinical Immunology; Journal of Allergy in Practice; Annals of Allergy, Asthma & Immunology; and Allergy Proceedings. Dr. Bernstein is the recipient of many awards, including the Distinguished Clinician Awards from the AAAAI and World Allergy Organization (2019). He is currently an author or coauthor of over 510 scientific articles and five books pertaining to asthma, rhinitis, and immunodeficiency. Dr. Bernstein is actively involved with the University of Cincinnati Allergy Fellowship Training Program in the education of fellows and also teaches residents and medical students. Dr. Bernstein has been voted “Best Doctor” in Cincinnati from 1999 to 2025 by Cincinnati magazine and has been ranked by US News & World Report as being in the top 1% of doctors in his specialty. He is director or codirector for several centers of excellence in Cincinnati, including the WAO center of excellence, the American Initiative for Mast Cell Diseases (AIM), Urticaria Centers of Excellence and Reference (UCARE), Angioedema Centers of Excellence and Reference Care (ACARE), Atopic Dermatitis Centers of Excellence and Reference Care (ADCARE), and Anaphylaxis Centers of Excellence and Reference Care (ANACARE).

Mark L. Levy FRCGP did his medical training in South Africa where he lived until 1977. He has been a United Kingdom (UK) General Practitioner for over 45 years, was a GP trainer for 13 years and was an expert assessor for the National Clinical Assessment service in England for 6 years. He was a voluntary first line responder for the London Ambulance service for 6 years. His interest in respiratory disease started in medical school, followed by six months working in a respiratory intensive care unit in Johannesburg, and has since developed a special interest in asthma. He has authored & co-authored over 180 papers & six books on asthma. He was one of the six founder members, first chairman and past editor of the Primary Care Respiratory Society UK (formerly the GPIAG); currently Editor Emeritus for the Primary Care Respiratory Journal. He was Clinical Lead for the UK National Review of Asthma Deaths (NRAD) (2011–2014) and has since been expert witness for Coroners in preventable asthma deaths. He was a member of the UK acute asthma guidelines (BTS/SIGN) from 1992–2017; and is currently an Executive Board member and Chair of the Dissemination Task Group of the annually updated, evidence based, Global Initiative on Asthma (GINA www. ginasthma.org). He was Clinical Lead for the NHS England Data and Digital Transformation program workstream for children and young people and currently is an adviser for the UK All Party Parliamentary Respiratory Group on asthma, COPD and allergy.

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