Clinical Innovation in Rheumatology Past, Present, and Future
Tremendous advances have been made in the field of rheumatology, profoundly changing our understanding of many rheumatologic conditions and creating a new frontier for effective treatments. This book explains the most significant advances in research and care and speculates as to what will be the future of rheumatology over the next several decades, including challenges and lessons learned from past experiences in the field. It highlights landmark research articles and scientific discoveries, discusses how big data, personalized medicine, new biomarkers for disease, and other technological revolutions will shape the future, making it a must-have resource for physicians from all regions of the world.
• Includes concise yet thorough description of the landmark studies and scientific breakthroughs coupled with easy-to-follow organizational structure of chapters that are accessible to readers at different levels of training.
• Brings together world-leading experts to provide a fresh perspective to trainees such as residents and fellows-in-training, as well as more senior clinicians and researchers across the field of rheumatology and in specialties such as cardiology, dermatology, pulmonology, nephrology, and neurology, all of whom care for patients with rheumatologic conditions.
• Allows the authors to imagine and speculate about the evolution of the field of rheumatology in the coming decades. Examples of such speculative possibilities include use of synovial biopsy to predict response to treatment in rheumatoid arthritis, replacement of renal biopsy with urinary proteomics in diagnosing and classifying lupus nephritis, use of new therapeutics to obviate the need for steroids in the treatment of ANCA-associated vasculitis, and the use of machine learning to evaluate subtle changes in imaging for management of inflammatory arthritis.
Chapter 1: Rheumatoid Arthritis
Brent A. Luedders, Ted R. Mikuls, James R. O’Dell and Bryant R. England
Chapter 2: Axial Spondyloarthritis
Ethan Craig and Alexis Ogdie
Chapter 3: Psoriatic arthritis
Elena Obreja, Ana-Maria Orbai and Jason Liebowitz
Chapter 4: Crystalline Arthritis
Gary H Ho and Michael Toprover
Chapter 5: Osteoarthritis
Marc C. Hochberg, Virginia Byers Kraus, Stefan Lohmander, Ali Guermazi, Frank Roemer and Ali Mobasheri
Chapter 6: Systemic Lupus Erythematosus
Vaneet K. Sandhu, Neha V. Chiruvolu, Daniel J. Wallace
Chapter 7: Sjogren’s Disease
Ghaith Noaiseh and Alan N. Baer
Chapter 8: Scleroderma
Julie J. Paik
Chapter 9: Myositis
Rasha Shahin and Eleni Tiniakou
Chapter 10: Vasculitis
Michelle Robinette, Eli Miloslavsky and Zachary S. Wallace
Chapter 11: Osteoporosis
Mazen Nasrallah and Marcy B. Bolster
Chapter 12: Immune-related Adverse Events: A Novel Paradigm of the Immune System
Pankti D. Reid and Anne R. Bass
Chapter 13: Complementary and Alternative Medicine Use in Rheumatic Disease
Sara Baig & Dana D. DiRenzo
Chapter 14: COVID-19 and MIS-C
Jordan E. Roberts, Mary Beth Son