Primary progressive aphasia is a type of dementia that progressively impairs language abilities (speaking, understanding, reading and writing) and may eventually affect other aspects of thinking, movement and/or personality. For the person with primary progressive aphasia, these problems have a profound effect on their ability to communicate, which in turn impacts their relationships, social networks and ability to participate in everyday activities that depend on communication. Recent understanding of primary progressive aphasia has grown enormously, however, and this book provides an up-to-date survey of research relevant to the clinical care of people with primary progressive aphasia. It covers initial diagnosis, neuropathology, genetics and typical patterns of progression from early- to late-stage disease, with a special focus on management and intervention for a range of different language symptoms and everyday communication activities.
This book is suitable for a wide readership, from neurologists, geriatricians and other medical specialists, to general practitioners, speech and language therapists, occupational therapists, psychologists and students in these fields. It was originally published as a special issue of the journal Aphasiology.
1. Introduction: Understanding and living with primary progressive aphasia: Current progress and challenges for the future Lyndsey Nickels and Karen Croot 2. Our journey with primary progressive aphasia Shirley Rutherford 3. Differential diagnosis of primary progressive aphasia variants using the international criteria Cristian E. Leyton and John R. Hodges 4. Biomarkers in the primary progressive aphasias Murray Grossman 5. The genetics of primary progressive aphasia Jonathan D. Rohrer 6. Longitudinal imaging and deterioration in word comprehension in primary progressive aphasia: Potential clinical significance Andreia V. Faria, Rajani Sebastian, Melissa Newhart, Susumu Mori, and Argye E. Hillis 7. The patterns of progression in primary progressive aphasia: Implications for assessment and management Michał Harciarek, Emilia J. Sitek, and Andrew Kertesz 8. Long-term follow-up in primary progressive aphasia: Clinical course and health care utilisation Lina Riedl, Dirk Last, Adrian Danek, and Janine Diehl-Schmid 9. Use of the Progressive Aphasia Severity Scale (PASS) in monitoring speech and language status in PPA Daisy Sapolsky, Kimiko Domoto-Reilly, and Bradford C. Dickerson 10. Motor speech disorders associated with primary progressive aphasia Joseph R. Duffy, Edythe A. Strand, and Keith A. Josephs 11. Grammatical impairments in PPA Cynthia K. Thompson and Jennifer E. Mack 12. Word retrieval therapies in primary progressive aphasia Regina Jokel, Naida L. Graham, Elizabeth Rochon, and Carol Leonard 13. Trouble and repair during conversations of people with primary progressive aphasia Cathleen Taylor, Karen Croot, Emma Power, Sharon A. Savage, John R. Hodges, and Leanne Togher 14. Dysgraphia in primary progressive aphasia: Characterisation of impairments and therapy options Naida L. Graham 15. Augmentation of spelling therapy with transcranial direct current stimulation in primary progressive aphasia: Preliminary results and challenges Kyrana Tsapkini, Constantine Frangakis, Yessenia Gomez, Cameron Davis, and Argye E. Hillis 16. Functional disability in primary progressive aphasia Claire M. O’Connor, Samrah Ahmed, and Eneida Mioshi
From being an area primarily on the periphery of mainstream behavioural and cognitive science, neuropsychology has developed in recent years into an area of central concern for a range of disciplines.
We are witnessing not only a revolution in the way in which brain-behaviour-cognition relationships are viewed, but also a widening of interest concerning developments in neuropsychology on the part of a range of workers in a variety of fields.
Major advances in brain-imaging techniques and the cognitive modelling of the impairments following brain injury promise a wider understanding of the nature of the representation of cognition and behaviour in the damaged and undamaged brain.
Neuropsychology is now centrally important for those working with brain-damaged people, but the very rate of expansion in the area makes it difficult to keep with findings from the current research.
The aim of the Brain, Behaviour and Cognition series is to publish a wide range of books that present comprehensive and up-to-date overviews of current developments in specific areas of interest.
These books will be of particular interest to those working with the brain-damaged. It is the editors' intention that undergraduates, postgraduates, clinicians and researchers in psychology, speech pathology, and medicine will find this series a useful source of information on important current developments.
The authors and editors of the books in the series are experts in their respective fields, working at the forefront of contemporary research. They have produced texts that are accessible and scholarly. We thank them for their contribution and their hard work in fulfilling the aims of the series.