1st Edition

Clostridioides difficile Diagnostic and Clinical Perspectives

164 Pages 6 Color & 8 B/W Illustrations
by CRC Press

164 Pages 6 Color & 8 B/W Illustrations
by CRC Press

164 Pages 6 Color & 8 B/W Illustrations
by CRC Press

This book is a practical guide for clinicians and other healthcare providers on a holistic approach to understanding and managing Clostridioides difficile infection. It covers pathophysiology, the role of the microbiome, diagnostic testing, management guidelines, and treatment options, including newly approved therapeutics. It also describes the patient experience and burden of C. difficile,... Read more

Preface

Editor Biographies

List of Contributors

Chapter 1 Clostridioides difficile–Restrictive and –

Permissive Gut Microbiomes: A Review

Farhan Anwar, Allison Nicole Sullivan, VK Viswanathan, and Gayatri Vedantam

Chapter 2 Clostridioides difficile Diagnostic Testing

Mark H. Wilcox and Kerrie Davies

Chapter 3 Diagnosis and Management of Clostridioides difficile in Patients with Inflammatory Bowel Disease

Alexander D. Carlin and Jessica R. Allegretti

Chapter 4 Antimicrobial and Biologic Therapeutics Utilized for the Treatment of Clostridioides difficile

Andrew M. Skinner and Emily N. Drwiega

Chapter 5 A Comparative Review of GI and ID Guidelines for Clostridioides difficile Treatment

Colleen R. Kelly

Chapter 6 Microbiota-Based Therapies for Clostridioides difficile

Sahil Khanna

Chapter 7 Transitions of Care Associated with Clostridioides difficile Infection

Amar Krishna and Teena Chopra

Chapter 8 Nursing and Patient Perspective Clostridioides difficile Infection

Candace Cotto

Chapter 9 The Health-Related Quality of Life Aspects of Clostridioides difficile Infection

Travis J. Carlson

Chapter 10 The Economics of Clostridioides difficile Infection: A Healthcare System Perspective

Nicholas Van Hise and Glenn Tillotson

Index

Biography

Glenn Tillotson, PhD, FIDSA, FCCP, is a Partner at GST Micro, a microbiologist consultant to the pharmaceutical and diagnostic industries. He provides support for both medical affairs and commercialization programs for companies, most notably in the infectious disease area.

Glenn has had a number of senior roles in the pharmaceutical industry, with over 40 years’ experience in clinical research, commercialization, and scientific communications, including publications planning, strategic drug development, life cycle management, and global launch programs.

Glenn has published over 230 articles; 5 textbook chapters; been a member of several editorial advisory boards, including Lancet Infectious Diseases; has been a member of scientific steering committees for a range of international congresses; and has been involved in several Clostridioides difficile programs. He is a fellow of Infectious Disease Society of America (IDSA) and American College of Chest Physicians and is currently Editor in Chief of the Expert Review of Anti-Infective Therapy journal.

Paul Feuerstadt, MD, FACG, AGAF, is a gastroenterologist practicing at the PACT Gastroenterology Center and is an Associate Clinical Professor of Medicine at the Yale School of Medicine.

Dr. Feuerstadt’s focuses include the microbiota, C. difficile infection, eosinophilic disorders, intestinal ischemia, and acute and chronic changes in bowel habits. He has been a principal investigator on numerous clinical trials in these spaces. Within his practice, he is very active in teaching and volunteer work locally and nationally for disease and discipline specific initiatives.

Dr. Feuerstadt has authored and coauthored many manuscripts and textbook chapters. Another passion of Dr. Feuerstadt’s is teaching, frequently giving lectures locally, regionally, nationally, and internationally. He works extensively with the gastroenterology fellows in the division of digestive disease at Yale-New Haven Hospital.

His clinical practice at the PACT Gastroenterology Center is his ultimate passion, filling the majority of his work time.

Nicolette Theriault, MPH, is a researcher and analyst in independent medical education outcomes, focusing on transforming data into actionable insights to improve medical education and patient outcomes.

She has a diverse background in health education programming, medical writing, and public health research; she brings a multidisciplinary approach to measuring impact. Nicolette has authored and coauthored multiple manuscripts in the infectious disease and medical education space.