1st Edition

Coccidiosis in Livestock, Poultry, Companion Animals, and Humans

Edited By J. P. Dubey Copyright 2020
    396 Pages 46 Color & 30 B/W Illustrations
    by CRC Press

    394 Pages 46 Color & 30 B/W Illustrations
    by CRC Press

    394 Pages 46 Color & 30 B/W Illustrations
    by CRC Press

    Coccidiosis is one of the most important diseases of livestock, particularly poultry, with billions of dollars spent on prevention worldwide. The disease is so important and pervasive that until recently, all poultry feed was medicated with coccidiostats, mainly antibiotics. With the rapid development of drug resistance, the search is on for alternative methods of control of coccidiosis in poultry. With chapters authored by internationally renowned scientists, this book covers coccidiosis in all major livestock species, including cattle, sheep, and goats. Special emphasis is given to poultry coccidiosis given the significant economic impact, and another chapter looks at intestinal coccidiosis in humans, including Cyclospora. Chapters discuss techniques, molecular biology, host-pathogen immunobiology and immunoprophylaxis, genetics and genomics, biology, and chemotherapy.

    Despite an explosion of research in the last 40 years, there has been no new book published discussing conventional coccidiosis for more than 25 years. This comprehensive review therefore answers an urgent need for a book dealing exclusively with conventional coccidia (Cystoisospora, Cyclospora). It provides concise, authoritative, up-to-date information on coccidiosis, with particular attention given to research in the last 28 years.

    This book is essential reading for any practitioner or researcher involved in livestock production, including biologists, veterinarians, parasitologists, and researchers from government, academia, and industry.

    Chapter 1 Biology of Intestinal Coccidia
    J. P. Dubey, D S. Lindsay, M. C. Jenkins, and C. Bauer
    Chapter 2 Phylogeny of Coccidian
    P. C. Thompson and B. M. Rosenthal
    Chapter 3 Host Immunity in Coccidiosis
    H. S. Lillehoj, W. H. Ki and A. Chaudhury
    Chapter 4 Vaccination
    M. C. Jenkins
    Chapter 5 Genomics, Transcriptomics, and Proteomics of the Eimeria Species
    D. Blake and F. Tomley
    Chapter 6 Anticoccidial Drugs of Livestock and Poultry Industries
    S. Noack, H. D. Chapman, and P. M. Selzer
    Chapter 7 Coccidiosis in Cattle
    B. Bangoura and A. Daugschies
    Chapter 8 Coccidiosis in Water Buffaloes (Bubalus bubalis)
    J. P. Dubey
    Chapter 9 Coccidiosis in Sheep
    J. M. Molina and A. Ruiz
    Chapter 10 Coccidiosis in Goat (Capra hircus)
    A. Ru and J. M. Molina
    Chapter 11 Coccidiosis of Pigs
    A. Joachim and A. Shrestha

    Chapter 12 Coccidiosis in Old World Camels
    J. P. Dubey and R. K. Schuster
    Chapter 13 Coccidiosis in South American Camelids
    J. P. Dubey
    Chapter 14 Coccidiosis in Rabbits (Oryctolagus cuniculus)

    M. Pak and X. Liu
    Chapter 15 Coccidiosis in Chickens (Gallus gallus)
    B. Jordan, G. Albanese, and L. Tensa
    Chapter 16 Coccidiosis in Poultry in China
    X. Suo
    Chapter 17 Coccidiosis in Turkeys (Meleagris gallopavo)
    T. Rathinam and U. Gadde
    Chapter 18 Coccidiosis in Ducks (Anas spp.)
    S. Wang and X. Suo
    Chapter 19 Coccidiosis in Horses and Other Equids
    C. Bauer and J. P. Dubey
    Chapter 20 Coccidiosis in Dogs (Canis familiaris)
    J. P. Dubey and D. S. Lin
    Chapter 21 Coccidiosis in Cats (Felis catus)
    J. P. Dubey
    Chapter 22 Coccidiosis in Humans
    S. Almer, H. N. Cinar, and J. P. Dubey




    J. P. Dubey, M V Sc, PhD, Dsc was born in India. He earned his veterinary degree in 1960, and Master in Veterinary Parasitology in 1963, from India. He earned a PhD in medical microbiology in 1966 from the University of Sheffield, England. Dr. Dubey received post doctoral training from 1968-1973 with Dr. J.K. Frenkel, Department of Pathology and Oncology, University of Kansas Medical Center, Kansas City. From 1973 to 1978, he was Associate Professor of Veterinary Parasitology, Department of Pathobiology, Ohio State University, Columbus and Professor of veterinary parasitology, Department of Veterinary Science, Montana State University, Bozeman, from 1978 to 1982. He is presently a Senior Scientist, Animal Parasitic Diseases Laboratory, Beltsville Agricultural Research Institute, Agricultural Research Service, United States Department of Agriculture, Beltsville, Maryland.

    Coccidiosis in Livestock, Poultry, Companion Animals and Humans is a long needed update and review for this group of clinically important protozoan parasites that infect a wide variety of hosts. It’s been 25 years since the coccidia were thoroughly reviewed with updated information so it’s timely and needed. The group of internationally recognized authors and subject matter experts have updated important aspects about Coccidiosis including detailed chapters on their biology, phylogeny, immunity, vaccination, modern molecular biology techniques, anticoccidial drugs, and new information on the coccidia of cattle. Coccidiosis in Livestock, Poultry, Companion Animals and Humans will be a must have comprehensive resource for a wide range of global scientific disciplines for upper level undergraduate and graduate students, and researchers that include veterinary parasitologists, veterinarians, physicians, clinicians, and animal and poultry scientists.

    -- Daniel E. Snyder, Veterinary Parasitology Consultant at ‘Daniel E. Snyder, DVM, PhD Consulting, LLC.’ October 2019


    This book focuses on the genera Eimeria, Cyclospora and Cystisospora, which are apicomplexan parasites, known as conventional coccidia, and cause coccidiosis. Coccidiosis is one of the most important diseases of livestock, particularly poultry, but occurs also in many other farm and companion animals, as well as in humans. Coccidiosis has a huge economic impact, and represents a constant threat to the food supply. The extensive use of coccidiostats, especially against Eimeria in poultry, has led to widespread drug resistance, and this problem needs to be solved in the years to come, as there are many challenges ahead in order to ensure food security, but also food safety, for an ever-growing population on this planet. A plethora of studies on different aspects of coccidian biology, phylogeny, pathogenesis and treatment and prevention strategies have been carried out and published during the last 20-30 years, and it has become difficult to keep track and maintain an overview of the research developments in the field. Thus, this book summarizes in a concise and very structured manner the current knowledge on coccidiosis caused by conventional coccidia, and as such fills an important gap.

    The driving force behind this book has been Dr. Jitender P. Dubey, which is clearly one of the most eminent parasitologists on this planet, and also known for his excellent books on Toxoplasma, Cryptosporidium, Sarcocystis and Neospora. Here, Dr. Dubey recruited scientists of high international reputation from all over the world to contribute chapters on the basic biology of coccidia, phylogeny, host immunity, vaccination, genomics, transcriptomics and proteomics, and on the current state of anti-coccidial drugs. These seven chapters provide an excellent and up-to-date overview on the covered subjects. The following chapters are dedicated to coccidiosis in the different major livestock species, including cattle, water buffaloes, pigs, sheep, goats, and most important, poultry. However, also other host species are covered, including camelids, rabbits, turkeys, ducks, horse and other equids, dogs, cats, and also humans. In these chapters the reader will encounter concise information on the different species of coccidia found in the different host species, the life cycle and morphological features, data on prevalence, on the pathogenesis, diagnosis, management and treatment options.

    The book also contains stunning illustrations, showing the morphological, histological and structural features of the different coccidia, and how infections affect their hosts and cause disease. In addition, many Tables are provided that summarize all this information in a concise and clear manner. Overall, I believe that this book represents an invaluable, highly useful resource and "must-have" for all interested in coccidian parasites, including students, biologists, veterinarians, parasitologists, government, academia and industry.

    -- Andrew Hemphill, Institute of Parasitology, Department of Infectious Diseases and Pathobiology, Universität Bern, Switzerland