Computational Genomics : Theory and Application book cover
1st Edition

Computational Genomics
Theory and Application

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ISBN 9781904933014
Published August 21, 2004 by Taylor & Francis
350 Pages 67 B/W Illustrations

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Book Description

This major new work is an invaluable laboratory manual for all scientists involved with computational genomics. Topics covered include database searches, sequence analysis and comparison, multiple sequence analysis, large-scale EST analysis, genome browsing, protein structure prediction, mircroarray data analysis, and proteomics. The book is also useful as a teaching reference for graduates and undergraduate students.

Table of Contents

1. Introduction to Sequence Analysis. 2. Sequence Databases. 3. Multiple Sequence Analysis Part I: An Introduction to the Theory and Application of Multiple Sequence Analysis. 4. Multiple Sequence Analysis Part II: a Practical Tour of SeqLab, the Accelrys GCG Wisconsin Package. 5. Hidden Markov Models: Principles and Applications. 6. Large scale EST analysis. 7. Genquire and Apollo: The Evolution of Genome Browsers. 8. Genquire and Apollo: Construction of a Genome 'Sandbox'. 9. Protein Structure Prediction. 10. Structure Databases/Proteomics Tools. 11. An Introduction to Microarray Data Analysis. 12. Jemboss - a Graphical Interface to EMBOSS. 13. SeWeR. 14. BioMOBY.

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Computational Genomics: Theory and Applications should be a valuable asset to any investigator struggling to keep up with the current status of publicly available data repositories and analytical tools, but requiring understanding of the logic behind the analysis. - Expert Review of Molecular Diagnosis, Volume 5, No. 4, 2005