The immune system is highly complex system with large number of macromolecules, signaling pathways, protein-protein interactions, and gene expressions. Studies from genomics, transcriptomics, metabolomics are generating huge high throughput data that needs to be analyzed for understanding the Immune system in Health and Disease. Computational approaches arehelping in understanding the study of complex biology of immunology and thereby enabling design of therapeutic strategies in diseases like infectious diseases, immunodeficiency, allergic, hypersensitive, autoimmune disorders and diseases like Cancer, HIV etc.
Computational Immunology: Basics highlights the basics of the immune system and function in health and disease.
This book offers comprehensive coverage of the most essential topics, including
- Overview of Immunology and computational Immunology
- Immune organs and cells, antigen, antibody, B, cell, T cell
- Antigen Processing and presentation
- Diseases due to abnormalities of the immune system
- Cancer Biology
Shyamasree Ghosh (MSc, PhD, PGDHE, PGDBI), is currently working in the School of Biological Sciences, National Institute of Science Education and Research (NISER), Bhubaneswar, DAE, Govt of India, graduated from the prestigious Presidency College Kolkata in 1998. She was awarded the prestigious National Scholarship from the Government of India. She has worked and published extensively in glycobiology, sialic acids, immunology, stem cells and nanotechnology. She has authored several publications that include books and encyclopedia chapters in reputed journals and books.
Table of Contents
Chapter 1 Overview of Immunology and Computational Immunology; Chapter 2 Immune Organs and Cells, Antigen, and Antibody, B-Cell, and T-Cell; Chapter 3 Antigen Processing and Presentation; Chapter 4 Innate Immunity; Chapter 5 Inflammation; Chapter 6 Infection and Immunity; Chapter 7 Transplantation Immunology; Chapter 8 Vaccines; Chapter 9 Diseases due to Abnormalities of the Immune System; Chapter 10 Cancer Biology
Dr. Shyamasree Ghosh (MSc, PhD, PGDHE, PGDBI) is currently working as the Scientific Officer (F), in the School of Biological Sciences, National Institute of Science Education and Research (NISER), Bhubaneswar, under Department of Atomic Energy, Govt of India currently located in Jatni, Orissa since 2016 dedicated to teaching and research. From 2009 she served as the Scientific Officer (E), in the SBS, NISER. She graduated from the prestigious Presidency College Kolkata in 1998 in Zoology with Chemistry and Physiology as the other subjects and was awarded the prestigious National Scholarship from the Govt. of India in the same year. She obtained post graduation degree in Biotechnology from Calcutta University ranking second in the University in the year 2000. She continued her PhD from Indian Institute of Chemical Biology, CSIR, Kolkata by qualifying for the National Eligibility Test conducted by Ministry of HRD, Govt of India. Her PhD work in the field of Childhood Acute Lymphoblastic Leukemia (ALL) was accepted in various national and international journals of repute and is cited by the young researchers worldwide. She has worked and published extensively in glycobiology, biology of sialic acids, immunology, stem cells and nanotechnology. She has served as faculty in post graduate college affiliated to Bangalore University. She has authored several publications that include books and encyclopedia chapters in reputed journals and books.
Research that tries to decode the complexity of life with hopes for a better living forms her research interest.