294 Pages
by Routledge

294 Pages
by Routledge

296 Pages
by Routledge

The fields of molecular biology and genetics are faced with an enormous accumulation of information: DNA sequencing, associated sequences of amino acids in proteins, genetics, macromolecular structures and other sets have created a quantitative backlog of data which needs to be organized and analyzed. Moreover, the rate of data acquisitions is accelerating as improved technologies are used and as... Read more
Preface , Introductory , The Human Genome: An Introduction , Computation and the Human Genome Project: An Historical Perspective , What We Have Learned and Will Learn from Sequence Databases , Databases , The Flow of Nucleotide Sequence Data into Data Banks: Role and Impact of Large-Scale Sequencing Projects , DNA Data Bank of Japan: Present Status and Future Plans , BIONET: Status and Future Plans , The Human Gene Mapping Library: Present Status and Future Directions , Sequence Comparisons , High-Efficiency Sequence Database Searching: Use of the Distributed Array Processor , Sequence Searching on Supercomputers , Protein Sequence Comparison on the Connection Machine CM-2 , Computation of d 2: A Measure of Sequence Dissimilarity , Multiple Hypothesis Testing for Sequence Comparisons , Analysis , Superhelical Transitions and DNA Regulation , Non-Continuous Patterns and Compositional Complexity of Nucleic Acid Sequences , Application of Neural Networks and Other Machine Learning Algorithms to DNA Sequence Analysis , CPGA 1 : A Prototype for Analysis of the Sequence-Structure-Function Relationship in the Human Genome Project , Statistical of Nucleic Acid Sequences , GeneSys: A Knowledge Management System for Molecular Biology , Simulation and Analysis of Physical Mapping , Genetic Sequence Semantic and Syntactic Patterns

Biography

Thomas Marr