The term phytomedicine was coined by French physician Henri Leclerc in 1913. Till recently phytomedicine has remained in the background. But due to emerging challenges to the conventional pharmaceutical industry (cost effectiveness and potency of the drugs), phytomedicine has made a dramatic comeback. Phytomedicine has witnessed several changes and several new concepts have been introduced. Phytomedicine, although, a separate discipline, is strongly linked to Phytotherapy and Phytopharmacology.
As the title suggests the book is an attempt to bridge the gap between fundamental and emerging concepts in this field of medicine. The book has been divided into two parts.
Part A deals with core issues of the phyto-pharmaceutical drug industry. The book begins with an introductory chapter dealing with basic definitions with phytomedicine. Chapters 2-5 narrate emerging subjects such as Phytopharmacovigilance, Phytopharmacoeconomics, Phytopharmacoepidemiology and Phytopharmacogenomics. Chapter 6 discusses ethical issues in phytomedicine. Chapter 7 covers recent advances in drug delivery systems in phytomedicine whereas Chapter 8 is about application of nanotechnology in the field of phytomedicine. The further chapters cover metabolomics, regulatory and legal aspects of the phyto-pharmaceutical drug industry. The chapter on herbal bioavailability enhancing agents is the salient feature of Part-A.
Part B is related to applied research in the field of phytomedicine. Experimental findings on phyto-bioactive agents such as withanolides, steroidal alkaloids, phytosteroids and phytocannabinoids have been elaborated.
Nine annexures related to herbal drug registration are included.
Table of Contents
Industrial Aspects of Phytomedicine. Introduction to Phytomedicine. Phytopharmacovigilance. Phytopharmacoeconomics. Phytopharmacoepidemiology. Phytopharmacogenomics. Ethics in Phytomedicine. Herbosomes. Nanophytomedicine. Metabolomics and Phytomedicine. Clinical Research in Ayurveda. Excepients for Phytomedicine. Certifications for Phytodrug Industry. Dhsea. Acts Related to Banned or Restricted Phyto Ingredients. Comfrey Based Herbal Products. Herbal Bioenhancers. Bioactives from Phytomedicine. Phytosteroids and Related Compounds. Botany Of Phytosteroids Containing Medicinal Plants. Pharmacology of Β-Sitosterol and Other Sterols. Pharmacology of Disogenin and Related Compounds. Steroidal Alkaloids. Guggulsterones. Phytoecdysteroids. Botany of Withanolides Containing Medicinal Plants. Pharmacology of Withaferin A. Pharmacology of Withanolide A. Pharmacology of Withanone. Pharmacology of Withanolide D. Miscellaneous Withanolides. Sitoindosides. Pyrrolizidine Alkaloids. Phytocannabinoids. Wild Cannabis. Annexures (1-9) Related to Herbal Drug Registration. Acronyms and Abbrevations. Definitions. Herbal Glossary.
Dr. Amritpal Singh completed his Bachelor’s and Master’s degree in Ayurveda (a system of traditional Indian medicine) from Guru Nanak Dev University, Amritsar, India and B.R. Ambedkar Bihar University, Muzaffarpur, India respectively. He also holds an MSc degree in Medicinal Plants from Nagaland Open University, Nagaland and has done specialized courses in phytochemical techniques, medicinal botany and ethnopharmacology.
He started his career as an Ayurvedic Medical Officer and later became an herbal consultant. He subsequently joined as external faculty at the National Institute of Pharmaceutical Education and Research, Mohali, Punjab and became a Senior Lecturer in Lovely Professional University, and at Dhanwantari Ayurvedic College, Chandigarh. Presently he is consultant to several national and international organizations. He has authored more than 20 books and presented more than 100 papers in Indian and international seminars and conferences. His work on herbal medicinal plants has earned him recognition.