1st Edition

Cryopreservation Applications in Pharmaceuticals and Biotechnology

Edited By Kenneth E. Avis, Carmen M. Wagner Copyright 1999
504 Pages
by CRC Press

504 Pages
by CRC Press

This book covers the principles of cryopreservation as they relate the preservation of viable cells and cell materials being developed for biopharmaceutical applications. Topics include: the principles of freezing and thawing cells, physiochemical phenomena, process and system design options, method selection considerations, preservation procedures, cryoprotectant additives, freeze-drying human... Read more
Contents include: Principles & Scale-up: Cryopreservation for Cells, Microorganisms, Protein Solutions, Biopharmaceutical Formulations, & Biological Products. Large-Scale Cryopreservation: Process Development for Freezing & Thawing of Large Volumes of Cell Suspensions, Protein Solutions & Biological Products. Methods: Long-Term Preservation of Mammalian Cells & Microorganisms. Cryopreservation of Mammalian Cell Culture Materials. Freeze-Drying of Human Live Virus Vaccines. The Design & Use of Thermal Transport Containers.

Biography

Kenneth E. Avis , Carmen M. Wagner