1st Edition
Curative and Preventive Properties of Medicinal Plants Research on Disease Management and Animal Model Studies
This book provides scientific reports on the therapeutic potential of medicinal plants using animal models and provides information on the beneficial role of medicinal plants on human diseases. It looks at a number of medicinal plants and examines the medicinal properties and activities of the plants for a variety of health issues, such as for diabetes, cardiovascular disease, neurodegenerative disease, organ dysfunctions, cancer, labor and postpartum issues, and more. The therapeutic mechanisms of some phytoconstituents are also discussed.
PART 1: POTENTIAL OF MEDICINAL PLANTS IN METABOLIC DISEASES
1. Leaf Extract of Dombeya buettneri for Inhibition of Inflammatory Cytokines Aggregation in Type-2 Diabetes
Esther Emem Nwanna, Olusola Olalekan Elekofehinti, Festus Igbe, and Adebola Oluwayemisi Ayeni
2. Antidiabetic Potential of African Medicinal Plants: A Brief Review Using Animal Models
Gbolahan Iyiola Asejeje and Folake Olubukola Asejeje
3. In vitro Antioxidant and Nephroprotective Activities of Carica papaya Methanol Extracts Using Streptozotocin-Induced Diabetic Male Albino Rats
Modupe Olusola Adetayo, Oluwaseyi Adegoke Adetunji, Babafemi Tosin Ogunbiyi, Gogonte Hezekiah Amah, Omowunmi O. Akinnawo, Laide O. Olajide, and Toyosi S. Ajiboye
4. Potential of Moringa oleifera for Prevention of Cardiovascular Diseases in Animal Models
Olufemi Idowu Oluranti
5. Blood Sugar Regulation and Pro-Inflammatory Effects of Desplatsia dewevrei in Streptozotocin-Induced Diabetic Wistar Rats
Oghale O. Godwin and MacDonald Idu
PART II: POTENTIAL OF MEDICINAL PLANTS IN NEURODEGENERATIVE DISEASES
6. Plant-Based Antioxidants in the Prevention and Treatment of Neurodegenerative Diseases: Pros and Cons
Folake Olubukola Asejeje and Gbolahan Iyiola Asejeje
7. Neuroprotective Efficacy of Ethnomedicinal Plants in Mental Disorders with Animal Models
Adedamola Aminat Bayo-Olugbami, Joseph Enya, and Olorunfemi Samuel Tokunbo
8. Translational Neuroprotective Activity of Curcumin in Neurodegenerative Diseases: An Overview with Animal Models
Adedamola Aminat Bayo-Olugbami, Kawkab Mujahidah Babalola, and Aminat Omolola Imam-Fulani
PART III: POTENTIAL OF MEDICINAL PLANTS IN ORGAN DYSFUNCTIONS
9. Multiple Organ Dysfunction Syndrome: Phytotherapeutic Evidence from Intestinal Ischemia-Reperfusion Models
Akinleye Stephen Akinrinde and Joseph Fadeyemi Akinrinmade
10. Biochemical Constituents and Toxicological Effects of Syzygium aromaticum on Selected Organs in Male Wistar Rats
Mosebolatan Victoria Adegbola, Ademola Olabode Ayeleso, and Temitope Adenike Oyedepo
11. Therapeutic Mechanisms of Bioactive Compounds in Lipopolysaccharide-Induced Liver Injury with Murine Models
Ayokanmi Ore, Ebenezer Tunde Olayinka, Babajide Oluwaseun Ajayi, and Oluseyi Adeboye Akinloye
12. Telfairia occidentalis for the Alteration of Expression Ratio of Bax/Bcl-2 mRNA in Lead-Exposed Rat Testicular Tissues
Adefolaju Gbenga Anthony, Falana Benedict Abiola, Odukoya Samson Ayodeji, and Mwakikunga Anthony
PART IV: HEALTH BENEFITS OF MEDICINAL PLANTS
13. Hydro-Ethanolic Leaf Extract of Parquetina nigrescens: Hematological Indices and Biochemical Parameters in Male Wistar Rats
Lydia Oluwatoyin Ajayi, Ademola Olabode Ayeleso, and Temitope Adenike Oyedepo
14. Role of Phytochemicals in Allium sativum on Obesity: A Review
Ayodeji Emmanuel Adepoju, Gregory Joseph, Samuel Olufolarin Babarinde, and Ademola Olabode Ayeleso
15. Antidiabetic Potency of Tofu (Soybean Meal)
Modupe Olusola Adetayo, Maria Onomaghuan Ebesunun, Olugbenga Obajimi Adebawo, Adekunle Moses Adetayo, Ifeoluwa Opeyemi Alao-Owunna, and Samuel Adegoke Adewole
16. Antioxidant Potential of Seed and Leaf Extracts of Adansonia digitata
Adetoun Elizabeth Morakinyo, Samuel Chibueze Nzekwe, Samuel Olufolarin Babarinde, Oluwatosin Elijah Olopade, Abraham Yakubu, and Ifeoluwa Dorcas Adegbite
17. Antioxidant, Anti-inflammatory, and Thrombolytic Activities of Monodora tenuifolia, Benth Seed Extract
Ademola Olabode Ayeleso, Olagunju Doris Imuetiyanosa, Samuel Chibueze Nzekwe, and Oluokun Oluboade Oyedapo
18. Effects of Taraxacum officinale Extract on Hematological Parameters in Female Wistar Rats with Ethanol-Induced Toxicity
Ademola Olabode Ayeleso, Samuel Chibueze Nzekwe, Favour Oghenefejiro, Samuel Olufolarin Babarinde, and Ayodeji Emmanuel Adepoju
19. Antimutagenic Activity of Moringa oleifera Seeds
Temitope Abiola, Olakunle Akinyode, Bisola Jimoh, Babawale Emmanuel Abiola, Ibukun Temitope Sossou, Adedayo Olukanni, and Olumide Olukanni
20. Scope of Medicinal Plants for Uterotonic, Tocolytic, and Wellness Effects in Pregnant Women: A Cultural Perspective
Hertha Kasiku Haikera, Larai Aku-Akai, and Yapo Guillaume Aboua
21. Role of Phytonutrients in Chemoprevention of Cancer: A Review
Oluwaseyi Adegoke Adetunji, Modupe Olusola Adetayo, Babafemi Tosin Ogunbiyi and Gogonte Hezekiah Amah
Biography
Megh R. Goyal, PhD, PE, is a prolific author and editor. He is a retired Professor from the College of Engineering at the University of Puerto Rico. A former soil conservation Inspector, Dr.Goyal was proclaimed as the "Father of Irrigation Engineering in Puerto Rico for the twentieth century" by the ASABE, Puerto Rico Section, for his pioneering work on micro irrigation, evapotranspiration, agroclimatology, and soil and water engineering. He has authored more than 200 journal articles and edited over 100 books.
Junaid Ahmad Malik, PhD, is a Lecturer with the Department of Zoology at Government Degree College, Bijbehara, Kashmir (J&K), India. He has more than eight years of research experience in ecology, soil macrofauna, wildlife biology, conservation biology, etc. Dr. Malik has published more than 20 research articles and technical papers in international peer-reviewed journals and has authored and edited books, book chapters, and popular editorial articles. He has participated in international conferences, seminars, workshops, and symposia.
Ademola Olabode Ayeleso, PhD, is a Professor of Biochemistry at Bowen University, Iwo, Nigeria; and Honorary Professor in the Department of Life and Consumer Sciences, University of South Africa, South Africa. He is a member of Adeleke University 2020–2025 strategic plan drafting committee to appraise all research and academic activities. At Adeleke University (Nigeria), he established a research group named DrosophilaAU Research Group, in which fruit flies (Drosophila melanogaster) are being used as a model to study diabetes and obesity. Dr. Ayeleso is actively involved in life research and has taught several courses in biochemistry. He is a prolific writer with about 40 publications to his credit.
