1st Edition

Cutting-edge Technologies in Biological Sensing and Analysis

Edited By Anh Hung Nguyen, Sang Jun Sim, Hung Cao Copyright 2023
    346 Pages 67 Color & 5 B/W Illustrations
    by River Publishers

    346 Pages 67 Color & 5 B/W Illustrations
    by River Publishers

    Advanced technologies have been transforming the ways we carry out biological studies as well as deliver healthcare. While micro- and nano-fabrication have provided miniaturized sensors and systems with better sensitivity and selectivity,; innovations in flexible electronics, biomaterials and telecommunications have helped in enabling novel biomedical devices, reducing cost, bringing convenience and establishing mobile-health (m-Health), and personalized- and tele-medicine. Further, the recent rise of the internet of things (IoTs) and machine learning-based approaches has paved the avenue for those biomedical systems to become popular and widely accepted by our society.

    In this context, we edit this book aiming to cover a broad field of novel technologies used in biological assessment and analysis for humans, animal models and in vitro platforms, in both health monitoring and biological studies.

    Technical topics discussed in the book include:

    • Biosensing systems and biomedical techniques
    • Imaging techniques and systems
    • Biosignal analysis
    • Animal models used in biological research

    1. Plasmonic sensors for applications in liquid biopsies

    Jong Uk Lee and Sang Jun Sim

    2. Analysis methods and clinical applications of circulating cell-free DNA and RNA in human blood

    Josiah T. Wagner, Josephine Briand, and Thuy T. M. Ngo

    3. Animal models and techniques used in cardiovascular research

    Jimmy Zhang, Samantha Lauren Laboy-Segarra, Anh H. Nguyen, Juhyun Lee, and Hung Cao

    4. Phage based biosensors

    Aarcha Shanmugha Mary, Vinodhini Krishnakumar, and Kaushik Rajaram

    5. Methods and challenges of tissue clearing engineering for tissue complexity

    Anh H. Nguyen, Donna H. Tran, and Hung Cao

    6. Novel imaging contrast agents and systems for biomedical sensing

    Shuai Yu and J.-C. Chiao

    7. Species-Independent Pipeline for Quantitative Analysis of Electroencephalogram with Application in Classification of Traumatic Brain Injury in Mice and Humans

    Manoj Vishwanath, Carolyn Jones, Miranda M. Lim, and Hung Cao

    8. Novel Image processing to restore scattered light-sheet microscopic imaging technique and its application for quantifying biomechanics

    Cynthia Dominguez, Tanveer Teranikar, and Juhyun Lee

    9. Assessment of cardiac functions in developing zebrafish using imaging techniques

    Amir Mohammad Naderi, Daniel Jilani, and Hung Cao


    Anh Nguyen is a research scientist for The HERO Laboratory in University of California, Irvine. He received his Ph.D. degree in Chemical and Biological Engineering under the supervision of Dr. Sang Jun Sim. He joined The HERO Lab in 2019 and was promoted to his current position in 2020, working in cardiac regenerations and biosensor engineering. He has published articles in biosensors, molecular biology, and protein engineering.

    Sim Sang Jun is a Professor of Chemical and Biological Engineering, Korea University, South Korea. He is a renowned leader in biosensors.

    Hung Cao is an Associate Professor of Electrical Engineering, Biomedical Engineering, and Computer Science at UC Irvine. He is one of the pioneers in developing systems to assess the biomedical signals in zebrafish and rodent models. He directs the HERO Laboratory at UC Irvine.