DNA Arrays: Technologies and Experimental Strategies, 1st Edition (Hardback) book cover

DNA Arrays

Technologies and Experimental Strategies, 1st Edition

Edited by Elena V. Grigorenko

CRC Press

184 pages | 16 Color Illus. | 76 B/W Illus.

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Hardback: 9780849322853
pub: 2001-12-21
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pub: 2001-12-21
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Description

A quantum leap in technology took place a few years ago with the introduction of cDNA arrays that have been developed in response to the need for simultaneous analysis of the patterns of expression of thousands of genes. DNA Arrays: Technologies and Experimental Strategies offers a view of different aspects of this rapidly developing technology, including oligonucleotide and electrochemical arrays. Distinguished investigators from academia and industry provide up-to-date insights into methodological fundamentals of construction of DNA arrays, optimization of hybridization conditions, the use of expression data in bioinformatics, software tools, and the application of microarray technology for drug discovery.

Table of Contents

Introduction

Technology Development for DNA Chips, H. Eickhoff, U. Schneider, E. Nordoff, L. Nyarsik, G. Zehetner, W. Nietfried, and G. Lehrach

Experimental Design for Hybridization Aray Analysis of Gene Expression, W. Freeman and K. Vrana

Nylon Platform: Pros and Cons, E. Grigorenko, S. Weber

Oligonucleotide Array Technologies for Gene Expression Profiling, D. Doris, R. Ramakrishnan, T. Sendera, S. Magnuson, and A. Mazumder

Electrochemical Detection of Nucleic Acids, R. Witwer, E. Espenhahn, M. Napier, and H. Thorp

DNA Microarrays in Neurobiology, M-C. Potier, B. Golfier, N. Cauli, B. Gibelin, B. Le Bourdelles, B. Lambolez, S. Kuhlmann, P. Marc, F. Devaux, and J. Rossier

Data Management in Microarray Fabrication, Image Processing and Data Mining, A. Kuklin, S. Shah, B. Hoff, and S. Shams

Zeroing In on Essential Gene Expression Data, S. Fuhrman, S. Liang, X. Wen, and R. Somogyi

Application of Arrayed Libraries for Analysis of Differential Gene Expression Followed Chronic Cannabinoid Exposure, E. Grigorenko, J. Kittler, and S. Deadwyler

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Index

About the Series

Frontiers in Neuroscience

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Subject Categories

BISAC Subject Codes/Headings:
SCI029000
SCIENCE / Life Sciences / Genetics & Genomics
SCI089000
SCIENCE / Life Sciences / Neuroscience