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Deep Brain Stimulation and Epilepsy




ISBN 9781841842592
Published November 13, 2003 by CRC Press
384 Pages 200 B/W Illustrations

 
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Book Description

Deep brain stimulation has been used effectively for many years to treat patients suffering from Parkinson's disease. Now, neurologists and neurosurgeons are using electric pulse generators to block abnormal activity, i.e. epileptic fits. Promising research results indicate that electric pulses implanted deep in the brain can affect neurocircuitry and help stop oncoming seizures. Supplying a solid background on brain stimulation and its application to epilepsy, Deep Brain Stimulation and Epilepsy provides a historical overview, explores pathogenesis of brain stimulation, discusses animal experiments and human studies, and explores future prospects of brain stimulation for epileptic control. The editor and his team of contributors distill information drawn directly from the literature into one convenient resource.

Table of Contents

HISTORICAL OVERVIEW: BRAIN STIMULATION AND EPILEPSY
Brain Stimulation and Epilepsy: Basic Overview and Novel Approaches, J. Lüders, I. Najm, and H.O. Lüders

PATHOGENESIS OF BRAIN STIMULATION: ANIMAL STUDIES
The Basal Ganglia: Overview, T. Subramanian
The Subthalamic Nucleus: Anatomy and Neurophysiology, T. Wichmann
Brain Stimulation and Epilepsy: Electrical Stimulus Characteristics, M.T. Rise
Electrically Excitable Nerve-elements: Excitation Sites in Peripheral and Central Stimulation, W.M. Grill
Control of Neuronal Activity by Electrical Fields: in vitro Models of Epilepsy, D.M. Durand and M. Bikson
The Nigral Control of Epilepsy: Basal Ganglia Circuitry as a Substrate for Seizure Control, K. Gale
High Frequency Direct Cortical Electrical Stimulation: An Animal Model of Induced Acute Focal Seizures, H. Shigeto, I. Najm, A. Boongird, D.R. Nair, C. Burrier, K.B. Baker, and H.O. Lüders

PATHOGENESIS OF BRAIN STIMULATION: HUMAN STUDIES
Cortico-cortical Evoked Potentials, R. Matsumoto, D.R. Nair, E. LaPresto, I. Najm, W. Bingaman, H. Shibasaki, and H.O. Lüders
Repetitive Transcranial Magnetic Stimulation, G. Thut and A. Pascual-Leone
High Frequency Subthalamic Nucleus Stimulation, E.B. Montgomery, J.R. Gale, and K.B. Baker
Cortical Evoked Potentials from Deep Brain Stimulation, K.B. Baker and E.B. Montgomery, Jr.
EEG Recording from the Subthalamic Nucleus in Patients with Epilepsy, D.S.Dinner, S. Neme, and H.O. Lüders
EEG and the Anterior Thalamic Nucleus, B, Litt and S. Cranstoun

EFFECT OF BRAIN STIMULATION ON EPILEPTIC SEIZURES: ANIMAL EXPERIMENTS
Absence Seizures in the GAERS Model: Subthalamic Nucleus Stimulation, A.-L. Benabid, L. Vercueil, K. Bressand, M. Dematteis, A. Benazzouz, L. Minotti, and P. Kahane
Focal Limbic Seizures Induced by Kainic Acid: Effects of Bilateral Subthalamic Nucleus Stimulation, A. Pan, A. Boongird, T. Kunieda, I. Najm, and H.O. Lüders
Focal Stimulation versus Deep Brain Stimulation, T. Tanaka, K. Hashizume, A. Matsuo, T. Urino, H. Tsuda, K. Kato, A. Hodozuka, and H. Nakai
The Anterior Thalamus and the Pentylenetrazol (PTZ) Model, M.A. Mirski, D.L. Sherman, and W.C. Ziai

EFFECT OF BRAIN STIMULATION ON EPILEPTIC SEIZURES: HUMAN STUDIES
Vagal Nerve Stimulation: Surgical Techniques, W.E. Bingaman
Vagal Nerve Stimulation: Effects on Seizures, D. Labar
Therapeutic Prospects and Safety of Transcranial Magnetic Stimulation in Epilepsy, F. Tergau and B. Steinhoff
Direct Cortical Electrical Stimulation in the Treatment of Epilepsy, D.R. Nair, R. Matsumoto, H.O. Lüders, R. Burgess, and W. Bingaman
Electical Neuromodulation of the Epileptic Focus in Caes of Temporal Lobe Seizures, F. Velasco, A.L. Velasco, M. Velasco, L. Rocha, and D. Menes
Anterior Thalamic Nucleus Stimulation: Surgical Procedure, G. Baluch
Anterior Thalamic Nucleus Stimulation: Issues in Study Design, R.S. Fisher
Surgical Procedure for Subthalamic Nucleus Stimulation, J.M. Rosenow, A. Boongrid, N.M. Boulis, A. Rezai
Subthalamic Nucleus and Substantia Nigra Pars Reticulata Stimulation: The Grenoble Experience, A.-L. Benabid, A. Koudsie, S. Chabardes, L. Vercueil, A. Benazzouz, L. Minotti, J.-F. Le Bas, P. Kahane, A. de Saint Martin, and E. Hirsch
Subthalamic Nucleus Stimulation in Patients with Intractable Epilepsy: The Cleveland Experience, S. Neme, E.B. Montgomery, Jr., A. Rezai, K. Wilson, and H.O. Lüders

BRIAN STIMULATION: FUTURE PROSPECTS
The Future of Brain Stimulation for Seizure Control, W. Heetderks

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Reviews

'This is the definitive account of the state of play of deep brain stimulation in epilepsy. It is a scholarly work, and covers the entire body of knowledge in this area, both in terms of animal and human studies. It is likely to be the definitive text in this specialised area.' - Highly Commended, Neurology Category, 2004 BMA Medical Book Competition

'This is a welcome addition for anyone interested in electrophysiology, epilepsy, and the therapeutic effects of electrical impulses.' - British Journal of Neurosurgery, Volume 102, June 2005