1st Edition

Deep Brain Stimulation for Parkinson's Disease

ISBN 9780849370199
Published March 19, 2007 by CRC Press
372 Pages 5 Color & 22 B/W Illustrations

USD $220.00

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Book Description

Considered the largest breakthrough in the treatment of Parkinson’s disease in the past 40 years, Deep Brain Stimulation (DBS) is a pioneering procedure of neurology and functional neurosurgery, forging enormous change and growth within the field. The first comprehensive text devoted to this surgical therapy, Deep Brain Stimulation for Parkinson's Disease expertly examines all aspects of DBS from history and theory to patient evaluation, recovery, and rehabilitation.


  • Serves as an invaluable resource and teaching guide for patient evaluation and the selection of candidates for surgery
  • Describes the surgical technique for DBS placement, reviewing both frame- and frameless-based approaches
  • Considers the morbidity and mortality associated with the procedure and details strategies for complication avoidance
  • Discusses pre- and post-operative management protocols, from the intensive care unit to rehabilitative settings
  • Outlines medication adjustment in the post-DBS patient for enhanced patient recovery, including illustrative case examples  
  • Reviews the effects of DBS surgery on speech, balance, autonomic function, sleep, and weight
  • Considers ethical and quality-of-life issues for DBS patients

Edited by specialists in the top-tiers of the discipline, including contributors from the pioneering Movement Disorder Group at the University of Pennsylvania, this is an indispensable companion for the entire neurological and neurosurgical community.

Table of Contents

The History of Deep Brain Stimulation.  DBS: Anatomical, Physiological, and Computational Mechanisms.  Indications for Subthalamic Nucleus DBS Surgery. Pre-op Assessment and Teaching. Surgical Technique for Leksell-Frame Based DBS of the Subthalamic Nucleus. Frameless Stereotaxy for Placement of Deep Brain Stimulators. Neurophysiology of the Microelectrode Track during Subthalamic Nucleus and Globus Pallidus Internus Targeting. Complications and Avoidance. Programming DBS. Medication Adjustment After DBS Surgery of the Subthalamic Nucleus. Rehabilitation after DBS.  DBS of the Subthalamic Nucleus. DBS for Parkinson’s Disease. Subthalamic Nucleus DBS and Nonmotor Symptoms of Parkinson's Disease.  Neuropsychology of DBS in Parkinson's Disease.  Neuropsychiatric Complications and DBS in Parkinson’s Disease. Quality-of-Life Outcomes Following Stereotactic Surgery for Parkinson’s Disease. Conducting Clinical Trials of DBS in Parkinson’s Disease. Ethical Issues in DBS.

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"This book would be a useful introduction for the novice and a good review for those more familiar with this topic." —Colin Watts (Addenbrooke's Hospital), Acta Neurochirurgica