Introduction to Dermatokinetics
Skin Tissue and the Extracellular Fluid
Fate of Therapeutic Agents in Skin
Distribution of Drugs in the Skin
Biochemistry of Cutaneous Tissue and Biotransformation of Drugs
Dermatokinetics of Drugs and Dermatopharmacology
Dermatokinetics of Drugs and Dermatotoxicology
Theoretical Models for Dermatokinetics of Therapeutic Agents
Introduction to Fundamentals of Pharmacokinetics
Theoretical Models of Dermatokinetics of Drugs
Two Compartment Model
Physiologically Based Pharmacokinetic Model
Drug Delivery Approaches to Modulate Dermatokinetics of Drugs
Drug Delivery Systems and Dermatokinetics
Salts, Prodrugs, and Complexes
Physiological Approaches to Dermatokinetics of Drugs
Cutaneous Sustained Release Drug Delivery Systems
Carrier Mediated Drug Delivery Systems
Physically Mediated Drug Delivery
Target Deliver to Skin
Conventional Methods of Cutaneous Drug Sampling
Introduction to Drug Sampling Techniques and their use in Dermatokinetics Studies of Drugs
Tape Stripping Method of Drug Sampling
Skin Biopsy Sampling
Skin Blister Fluid Sampling
Cutaneous Microdialysis
Basics of Cutaneous Tissue Microdialysis and Methods of Probe Calibration
Probes Used in Cutaneous Microdialysis
Common Procedural Issues, Troubleshooting, and Optimization Approaches
Sampling Substrates by Skin Permeablization
Introduction to Transcutaneous Sampling of Drugs
Reverse Iontophoresis
Electroporation Mediated Drug Sampling
Sonoporesis Mediated Sampling
Cutaneous Sampling by Microneedles
Spectroscopic Techniques in Dermatokinetics Studies
Introduction to Fundamentals of Spectroscopic Techniques Used in Dermatokinetics Studies
Fluorescence Detection Skin Drug Levels
ATR FTIR Detection of Drug in Skin
Raman Spectroscopy
Dermatokinetics of Gene Therapeutics
Gene Therapeutics and Cutaneous Gene Therapy
Pharmacogenetics of Gene Therapeutics in Skin
Regulatory Perspective of Dermatokinetic Studies
Skin Bioavailability and Bioequivalence Studies
FDA Guidelines for Dermatokinetic Studies
Biography
S. Narasimha Murthy is an Assistant Professor of Pharmaceutics at the University of Mississippi.
