1st Edition

Developmental Immunotoxicology

Edited By Steven D. Holladay Copyright 2005
384 Pages 50 B/W Illustrations
by CRC Press

Despite rapidly increasing interest in developmental immunotoxicology, there is not yet a textbook focused on this hot area of research. Developmental Immunotoxicology fills the void with overviews of immune system development in experimental animal and human models, and discusses the complex issues related to the evolution of developmental immunology and risk assessment. This text describes... Read more
DEVELOPMENT OF THE IMMUNE SYSTEM
Development of the Rodent Immune System; K.S. Landreth and S.V.M. Dodson
Development of the Human Immune System; R. Leibnitz

DEVELOPMENTAL IMMUNOTOXICOLOGY: MODELS
Risk Assessment Perspectives for Developmental Immunotoxicology; C.A. Kimmel, M.D. King, and S.L. Makris
The Mouse as a Model for Developmental Immunotoxicology; M.R. Prater, B.L. Blaylock, and S.D. Holladay
The Rat as a Model for Developmental Immunotoxicology; R.J. Smialowicz
The Pig as a Model for Developmental Immunotoxicology; H.J. Röthkotter, E. Sowa, and R. Pabst
The Non-Human Primate as a Model for Developmental Immunotoxicology; A.G. Hendrickx, P. Peterson, and N. Makori

DEVELOPMENTAL IMMUNOTOXICANT EXPOSURE AND POSTNATAL IMMUNOSUPRESSION
Developmental Immunotoxicology of Halogenated Aromatic Hydrocarbons and Polycyclic Aromatic Hydrocarbons; T.C. Hrubee, B.L. Blaylock, and S.D. Holladay
Developmental Immunotoxicity of Chlordane; J.B. Barnett, L.F. Gibson, and K.S. Landreth
Toxicity of Lead to the Developing Immune System; R.R. Dietert and J.-E. Lee
Developmental Immunotoxicity of Therapeutic Immunosuppressive Drugs; R.M. Gogal, Jr. and S.D. Holladay
Mycotoxins and Other Miscellaneous Developmental Immunotoxicants; T.C. Hrubec and S.D. Holladay

DEVELOPMENTAL IMMUNOTOXICANT EXPOSURE AND EXACERBATED POSTNATAL IMMUNE RESPONSES
Prenatal Immunotoxicant Exposure and Autoimmune Disease; B.L. Blaylock, S.A. Ahmed, and S.D. Holladay
Developmental Immunotoxicant Exposure and Exacerbated Postnatal Immune Responses: Asthma; J.M. Armstrong, R.R. Leibnitz, and D. Loer-Martin

NEUROIMMUNE INTERACTIONS
Developmental Neurotoxicity and Postnatal Immune Deficits; P.V. Basta
Neuroendocrine-Immune Interactions: Impact of Gender, Negative Energetic Balance Condition, and Developmental Stage on the Mechanisms of the Acute Phase Response of the Inflammatory Process in Mammals, E. Spinedi, N.B. Pérez, and R.C. Gaillard

Biography

Steven D. Holladay

"This book is the first to consider developmental immunotoxicology … an extremely important contribution to the toxicology literature. … [It] is also timely and provides a treatment of a major current scientific and regulatory issue … a text of high educational and reference value to toxicologists at all levels and across numerous disciplines. … [It] will undoubtedly be influential, as both science and regulatory risk assessment uncover the scale of a potential major human health problem."
- Journal of Applied Toxicology


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