Diabetes has garnered worldwide attention and research funding as clinicians and researchers seek to better understand its pathogenesis, prevention, complications management, and impact and relationship to other diseases (heart disease, kidney disease, infections, and inflammation). Clinicians are overwhelmed with rapidly evolving developments regarding the science and clinical management of diabetes and are struggling to understand and apply new diabetes information.
This book will provide a concise interpretation of translational diabetes research for the purpose of preparing clinicians to understand and effectively deploy new strategies and therapeutics into the clinical care of diabetes patients by examining:
the contrast between existing information in the clinical practice versus the basis and need for future clinical trials
breakthroughs within clinical trials and methods to incorporate bench to bedside material for the clinical practice
the synthesis and interpretation of the scientific principles, trial results, and clinical implications of emerging and translational therapies, and the management strategies for diabetic patients
the entire scope of translational diabetes research from biology to screening and prognosis, new therapeutics, insulin, transplantation, and complications management
new therapeutic strategies to knowledgeably and effectively equip the practicing clinician
assembles information that is scattered throughout the diabetic community into one concise single reference
Problems with the definition of diabetes: closing the gap between type 1 and type 2. How do we screen for and predict autoimmune diabetes? How do we screen for and predict autoimmune diabetes? How do we screen for and predict non-autoimmune diabetes? How do we screen for and predict non-autoimmune diabetes? What are the prospects for preventing autoimmune diabetes? How can we use genetic information in the clinic? Neural and endocrine control of satiety and energy metabolism. Insulin resistance; new approaches to detection and treatment. Adipokines. Incretins. Retinopathy. Cardiovascular disease. Transplantation. Creation and generation of B cells. Technologies for insulin delivery and glucose monitoring. Diabetes Complications: Molecules to Management.