Carefully crafted to provide tightly focused and authoritative information, the Directory of Therapeutic Enzymes covers all approved therapeutic enzymes currently used in medicine. Written mainly by industry experts, the book includes information sourced directly from the company that developed or manufactured the product. It explores major development issues, from manufacturing and marketing to delivery of the finished product.
Chapter 1 reviews applied enzymology while chapter 2 delineates theory and applications. Between them, the first two chapters set the appropriate backdrop for the remaining chapters, which focus on actual enzyme products that have gained regulatory approval for general medical use. The chapter authors discuss the biochemistry of the enzymes, the reactions they catalyze, how they are produced or manufactured, and their medical applications.
The book highlights the many applications of approved therapeutic enzymes, including use in the treatment of blood-clotting disorders, certain cancers, and a variety of genetic disorders. Illustrated with tables and figures that support the text, the book is a single source of in-depth technical information.
Table of Contents
Applied Enzymology, An Introduction. Enzyme Engineering. Tissue Plasminogen Activator (tPA). Urokinase. (Activated) Protein C. Ancrod. Nuclease (Dnase). Glucocerebrosidase. L-Galactosidase. Urate Oxidase. Asparaginase. Factor Ixa. Superoxide Dismutase. Debriding and Anti-Inflammatory Agents. Enzymes as Digestive Aids.
McGrath, Barry M. | Walsh, Gary