Dose-Response Analysis Using R: 1st Edition (Hardback) book cover

Dose-Response Analysis Using R

1st Edition

By Christian Ritz, Signe Marie Jensen, Daniel Gerhard, Jens Carl Streibig

Chapman and Hall/CRC

214 pages | 47 B/W Illus.

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Hardback: 9781138034310
pub: 2019-07-15
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Description

Dose-response analysis is a technique used to determine the safe and hazardous dosage of drugs, pollutants, and other substances to which humans and other organisms are exposed. This book provides a practical and comprehensive overview of methods for dose-response analysis. It includes many real data examples to illustrate the methods, and R code is integrated into the text to show how they are implemented. The book is supplemented by a website with all code and data, and has been written so as to be accessible to practitioners from biology and chemistry, as well as applied statisticians.

Table of Contents

Continuous data

Binary and binomial dose-response data

Count dose-response data

Multinomial dose-response data

Time-to-event-response data

Benchmark dose estimation

Hierarchical nonlinear models

Appendix A: Estimation

Appendix B: Dose-response model functions

Appendix C: More R Code

Bibliography, Index

About the Authors

Christian Ritz is an Associate Professor at the University of Copenhagen, Denmark.

Signe M. Jensen is an Assistant Professor at the University of Copenhagen, Denmark.

Daniel Gerhard is a Senior Lecturer at the University of Caterbury, New Zealand.

Jens Carl Streibig is Professor Emeritus at the University of Copenhagen, Denmark.

About the Series

Chapman & Hall/CRC The R Series

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Subject Categories

BISAC Subject Codes/Headings:
MAT029000
MATHEMATICS / Probability & Statistics / General
MED096000
MEDICAL / Toxicology