1st Edition
Drug Delivery From Fundamentals to the Future
List of Contributors
Editor/Author Bios
Chapter 01: Drug delivery systems (DDSs): from early development to modern ones
Antonio Lopalco, Rosa Maria Iacobazzi, Angela Assunta Lopedota, Nunzio Denora
Chapter 02: Physicochemical properties of drug substances
Emilia Jakubowska, Marcin Skotnicki
Chapter 03: Excipients and their role in drug formulation
Matthew P. Wylie
Chapter 04: Pre-formulation studies
Sebastian J Gurgul, Gareth R Williams
Chapter 05: Mechanism-Based Pharmacokinetic-Pharmacodynamic Modeling in Advanced Drug Delivery Systems
Kangna Cao, Xiaoyu Yan
Chapter 06: In vitro–In vivo Correlations (IVIVC)
Dorota Danielak, Michał Romański
Chapter 07: Pharmaceutical emulsions
Anna Froelich, Michał Gackowski
Chapter 08: Oral Solid Dosage Forms
Haja Muhamad, Ana-Maria Totea, Martin Rowland, Adeola Adebisi, Kofi Asare-Addo
Chapter 09: Bioadhesive buccal delivery systems
Adeola O. Adebisi, Rand Abdulhussain, Yusuf O. Ghazali, Kofi Asare-Addo
Chapter 10: Biologics Drug Delivery
Sheiliza Carmali, Leran Mao, Antonina Simakova
Chapter 11: Drug delivery systems: from nano to micro to macro
Giuseppe Francesco Racaniello, Ilaria Arduino, Vita D’amico, Nunzio Denora
Chapter 12: Nano-based gene delivery systems for engineering immune cells
Emma M. McErlean, Ciaran T. McGranaghan, Christopher L. Grigsby
Chapter 13: Injectable Drug Delivery
Rossella Dorati, Bice Conti
Chapter 14: Drug Delivery to the Central Nervous System
Tuba Oz, Małgorzata Kujawska
Chapter 15: Nasal Drug Delivery
Hussein Kenaan, Helmy Yusuf, Vicky Kett
Chapter 16: Pulmonary Drug Delivery
Vicky Kett, Yahya Dallal-Bashi
Chapter 17: Ocular Drug Delivery
Adrienn Kazsoki, Romána Zelkó
Chapter 18: Transdermal Drug Delivery
Tomasz Osmałek, Piotr Gadziński, Oliwia Kordyl
Chapter 19: Intravaginal Drug Delivery
Barbara Jadach
Chapter 20: Generic Drug Development & Biosimilars
Angeliki Siamidi, Chrystalla Protopapa, Panagoula Pavlou, Marilena Vlachou
Chapter 21: Personalised drug delivery systems
Tochukwu C. Okwuosa, Jasmine Southward, Atheer Awad
Chapter 22: Manufacturing of Sterile Pharmaceutical Products
James Agalloco
Chapter 23: Ensuring Quality of Pharmaceuticals: Regulatory and Quality by Design (QbD)
Rebecca Craig
Chapter 24: Machine learning and deep learning in drug delivery
Marcin Wierzbiński, Jacek Kujawski
Chapter 25: Sustainability in drug delivery: A green future
Aikaterini Dedeloudi, Dimitrios A. Lamprou
Chapter 26: Emerging Technologies in Drug Delivery
Rachel Milliken, Vlad-Nicolae Lesutan, Sune Andersen, Dimitrios A. Lamprou
Chapter 27: Advanced Characterization Techniques for Drug Delivery Systems: Tools and Applications
Sebastian J Gurgul, Gareth R Williams
Index
Biography
Professor Dimitrios A. Lamprou (Ph.D. MBA) is a subject matter expert in emerging pharmaceutical and biopharmaceutical technologies, with a focus on the development and manufacturing of sustainable drug delivery systems, advanced medical devices, and biocompatible implants. Currently, has authored more than 180 peer-reviewed publications and delivered over 200 invited talks at leading institutions and international conferences. His contributions to pharmaceutics and biomedical engineering have also earned him a place on Stanford University’s prestigious list of the world’s top 2% of scientists, an honour he has received for several consecutive years.
Dr Matthew Wylie (Ph.D., MPharm) is a Lecturer in Pharmaceutical Materials Science at the School of Pharmacy, Queen’s University Belfast. His research focuses on the design and characterisation of novel stimuli-responsive biomaterials and polymeric functional coatings for drug delivery applications, with a key interest in applying these responsive materials in clinical applications, such as targeted oral drug delivery, and the development of next-generation functional coatings for medical devices and implants. Currently, he has authored over 30 peer-reviewed publications and regularly presents his research at international conferences.
