1st Edition

Drug Delivery Nanoparticles Formulation and Characterization

Edited By Yashwant Pathak, Deepak Thassu Copyright 2009
    416 Pages 100 B/W Illustrations
    by CRC Press

    Exploring fundamental concepts, Drug Delivery Nanoparticles Formulation and Characterization presents key aspects of nanoparticulate system development for various therapeutic applications and provides advanced methods used to file for regulatory approval.

    This comprehensive guide features:

    • Process Analytical Techniques (PAT) used in manufacturing Nanoparticulate Drug Delivery Systems (NPDDS)
    • In-vitro and in-vivo evaluation of NPDDS
    • Applications of novel techniques used in formulation development and characterization, such as microscopic and nonmicroscopic techniques
    • 100 high-quality images

    Recent Developments in Nanoparticulate Drug Delivery Systems; Yashwant Pathak

    Polymeric Nanoparticles for Small-Molecule Drugs: Biodegradation of Polymers and Fabrication of Nanoparticles; Sheetal R. D’Mello, Sudip K. Das, and Nandita G. Das

    Formulation of NPDDS for Macromolecules; Maria Eugénia Meirinhos Cruz, Sandra Isabel Simões, Maria Luísa Corvo, Maria Bárbara Figueira Martins, and Maria Manuela Gaspar

    Formulation of NPDDS for Gene Delivery; Ajoy Koomer
    NPDDS for Cancer Treatment: Targeting Nanoparticles, a Novel Approach; Karthikeyan Subramani

    Design and Formulation of Protein-Based NPDDS; Satheesh K. Podaralla, Radhey S. Kaushik, and Omathanu P. Perumal

    Gold Nanoparticles and Surfaces: Nanodevices for Diagnostics and Therapeutics; Hariharasudhan D. Chirra, Dipti Biswal, and Zach Hilt

    NPDDS for the Treatment of Diabetes; Karthikeyan Subramani

    Nanosystems for Dermal and Transdermal Drug Delivery; Venkata Vamsi Venuganti and Omathanu P. Perumal
    In Vitro
    Evaluation of NPDDS; R. S. R. Murthy

    In Vitro Characterization of Nanoparticle Cellular Interaction; R. S. R. Murthy and Yashwant Pathak

    In Vitro Blood Interaction and Pharmacological and Toxicological Characterization of Nanosystems; R. S. R. Murthy and Yashwant Pathak

    In Vivo Evaluations of Solid Lipid Nanoparticles and Microemulsions; Maria Rosa Gasco, Alessandro Mauro, and Gian Paolo Zara

    Microscopic and Spectroscopic Characterization of Nanoparticles; Jose E. Herrera and Nataphan Sakulchaicharoen

    Introduction to Analytical Scanning Transmission Electron Microscopy and Nanoparticle Characterization; Zhiqiang Chen, Jinsong Wu, and Yashwant Pathak

    Structural Fingerprinting of Nanocrystals in the Transmission Electron Microscope: Utilizing Information on Projected Reciprocal Lattice Geometry, 2D Symmetry, and Structure Factors; Peter Moeck and Sergei Rouvimov

    Mechanical Properties of Nanostructures; Vladimir Dobrokhotov

    Fullerene-Based Nanostructures: A Novel High-Performance Platform Technology for Magnetic Resonance Imaging (MRI); Krishan Kumar, Darren K. MacFarland, Zhiguo Zhou, Christpher L. Kepley, Ken L.Walker, Stephen R. Wilson, and Robert P. Lenk

    Semiconducting Quantum Dots for Bioimaging; Debasis Bera, Lei Qian, and Paul H. Holloway

    Application of Near Infrared Fluorescence Bioimaging in Nanosystems; Eunah Kang, Ick Chan Kwon, and Kwangmeyung Kim



    Yashwant Pathak, Deepak Thassu