Duchenne Muscular Dystrophy: Advances in Therapeutics, 1st Edition (e-Book) book cover

Duchenne Muscular Dystrophy

Advances in Therapeutics, 1st Edition

Edited by Jeffrey S. Chamberlain, Thomas A. Rando

CRC Press

496 pages

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Hardback: 9780824723255
pub: 2006-02-27
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pub: 2006-02-27
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Duchenne Muscular Dystrophy (DMD) is one of the most prevalent genetic disorders of childhood and currently stands as an incurable condition. This authoritative guide provides a clear overview of the latest current and experimental approaches to the treatment of DMD and examines the clinical, genetic, and pathophysiological aspects of the disease i

Table of Contents

Clinical Overview. The Functional Biology of Dystrophin. Duchenne Muscular Dsytrophy and Becker Muscular Dystrophy: Diagnostic Principles. Mutation Detection. Protein Studies. Medical Management. Rehabilitation Management. A Review of Current Practice and Clinical Outcomes. Therapeutic Principles and Challenges. Experimental Pharmacologic Therapies. Utrophin: The Intersection between Pharmacological and Genetic Therapy. Regenerative Therapy. Cellular-Mediated Delivery: The Intersection between Regenerative Medicine and Genetic Therapy. Oligonucleotide-Mediated Rxon Skipping and Gene Editing. Intravascular Delivery of Naked DNA. Adenoviral-Mediated Gene Therapy. Retroviridae-based Gene Transfer Vectors. Gene Therapy Using Adeno-Associated Viral Vectors. Regional and Systemic Gene Delivery using Viral Vectors.

Subject Categories

BISAC Subject Codes/Headings:
MEDICAL / Neurology
MEDICAL / Neuroscience
MEDICAL / Genetics