Through a biophysical approach, Electromagnetic Fields in Biology and Medicine provides state-of-the-art knowledge on both the biological and therapeutic effects of Electromagnetic Fields (EMFs). The reader is guided through explanations of general problems related to the benefits and hazards of EMFs, step-by-step engineering processes, and basic results obtained from laboratory and clinical trials.
Basic biological mechanisms reviewed by several authors lead to an understanding of the effects of EMFs on microcirculation as well as on immune and anti-inflammatory responses. Based upon investigational mechanisms for achieving potential health benefits, various EMF medical applications used around the world are presented. These include the frequent use of EMFs in wound healing and cartilage/bone repair as well as use of EMFs in pain control and inhibition of cancer growth.
Final chapters cover the potential of using the novel biophysical methods of electroporation and nanoelectroporation in electrochemotherapy, gene therapy, and nonthermal ablation. Also covered is the treatment of tendon injuries in animals and humans. This book is an invaluable tool for scientists, clinicians, and medical and engineering students.
Table of Contents
Biological Windows: A Tribute to Ross Adey
Marko S. Markov
Replication and Extension of Adey Group's Calcium Efflux Results
Benefit and Hazard of Electromagnetic Fields
Marko S. Markov
Pulsed Electromagnetic Fields: From Signaling to Healing
Arthur A. Pilla
Biophysical Mechanisms for Nonthermal Microwave Effects
Engineering Problems in Bioelectromagnetics
Signal Design: Step by Step
James G. Seal
Magnetic Field Influences on the Microcirculation
Chiyoji Ohkubo and Hideyuki Okano
Extremely High-Frequency Electromagnetic Fields in Immune and Anti-Inflammatory Response
Andrew B. Gapeyev
Effects of Therapeutic and Low-Frequency Electromagnetic Fields on Immune and Anti-Inflammatory Systems
Walter X. Balcavage, Gabi N. Waite, and Stéphane J.-P. Egot-Lemaire
Effect of PEMF on LPS-Induced Chronic Inflammation in Mice
Juan Carlos Pena-Philippides, Sean Hagberg, Edwin Nemoto, and Tamara Roitbak
Computational Fluid Dynamics for Studying the Effects of EMF on Model Systems
Traikov, I. Antonov, E. Dzhambazova, A. Ushiama, and Chiyoji Ohkubo
Cell Hydration as a Marker for Nonionizing Radiation
Sinerik Ayrapetyan, Naira Baghdasaryan, Yerazik Mikayelyan, Sedrak Barseghyan, Varsik Martirosyan, Armenuhi Heqimyan, Lilia Narinyan, and Anna Nikoghosyan
Age-Dependent Magnetic Sensitivity of Brain and Heart Tissues
Armenuhi Heqimyan, Lilia Narinyan, Anna Nikoghosyan, and Sinerik Ayrapetyan
Electromagnetic Fields for Soft Tissue Wound Healing
Harvey N. Mayrovitz
Physical Regulation in Cartilage and Bone Repair
Ruggero Cadossi, Matteo Cadossi, and Stefania Setti
Magnetic Fields for Pain Control
Electromagnetic Fields in Plastic Surgery: Application to Plastic and Reconstructive Surgical Procedures
Christine H. Rohde, Erin M. Taylor, and Arthur A. Pilla
Daily Exposure to a Pulsed Electromagnetic Field for Inhibition of Cancer Growth: Therapeutic Implications
Ivan L. Cameron, Marko S. Markov, and W. Elaine Hardman
Nonionizing Radiation: Exposure Assessment and Risk
Michel Israel, M. Ivanova, V. Zaryabova, and T. Shalamanova
Environmental and Safety Aspects of the Use of EMF in Medical Environment
Long-Term, Low-Intensity, Disparate Electromagnetic Fields: Influence on Physiotherapy Personnel Morbidity Profile
Nanoelectroporation for Nonthermal Ablation
Electroporation for Electrochemotherapy and Gene Therapy
Maja Cemazar, Tadej Kotnik, Gregor Sersa, and Damijan Miklavcic
Dirty Electricity within the Intermediate-Frequency Range: The Possible Missing Link Explaining the Increase in Chronic Illness
Electromagnetic Fields in the Treatment of Tendon Injury in Human and Veterinarian Medicine
Richard Parker and Marko S. Markov
Marko S. Markov received his PhD from Sofia University in Bulgaria. He was a professor and chairman of the Department of Biophysics and Radiobiology there for more than 20 years. He also was the vice president for research and development in three US companies. Dr. Markov is recognized as a top world expert on the clinical application of electromagnetic fields. He has more than 30 years of experience in basic science research and the clinical application of electromagnetic fields for the treatment of pain as well as bone and soft tissue pathologies. Dr. Markov has written and edited 14 books, presented 282 papers and short communications at various international meetings, and published 192 scientific articles. He holds five international patents for the clinical and technological use of electromagnetic fields.
"This book was arranged and edited by Dr. Marko Markov—one of the most respected individuals in the area of bioelectromagnetics. ... presents the state-of-the-art use of EMF in clinical practice for resolving problems that conventional medical practice cannot successfully treat, providing the reader with a biophysical approach to the discussed problems ... It covers a large spectrum of problems related to the interactions of EMFs with living systems and the clinical benefits of such interactions. ... a helpful textbook for medical and bioengineering students ..."
—Yuri Grigoriev, Russian National Committee of Non-Ionizing Radiation Protection, Moscow
"… covers a range of research topics from the basic physics and interactions between EMF and biological systems to its clinical applications. The topics selected for inclusion reflect the growth of interest in this area."
—Betty F. Sisken, Professor Emeritus, Department of Anatomy and Neurobiology, University of Kentucky, Lexington
"… a well-balanced collection of articles …"
—Alex Thomas, PhD, CIHR-SME Chair