1st Edition

Endothelial Cell Plasticity in the Normal and Injured Central Nervous System

    272 Pages 18 Color & 4 B/W Illustrations
    by CRC Press

    This book highlights the importance of endothelial cells as key players in the functioning of the nervous system under both normal and pathological conditions. The book demonstrates that endothelial cells are an essential and dynamic cell population in the central nervous system, with multiple and complex roles, not only in the maintenance of homeostasis, but also in the regulation of important processes. These include neurogenesis, neural control of reproduction, aging, neurodegeneration, and tumor invasion. The book exhaustively reviews the newest findings in this exciting new area of investigation.

    Embryonic Development of the Brain Vascular System

    Endothelial Cells and Maintenance of Neurogenic Niches during Embryonic Development and Adult Life

    Alterations of Brain Endothelial Cells in Drug-Resistant Epilepsy: Drug Transporters

    Dynamic Control of Endothelial Cells in Neural Reproduction Centers

    Blood Vessel Remodeling After Stroke

    Systemic Vascular Alterations and Neurodegenerative Diseases

    Endothelial Cells, Alzheimer Disease and Metabolic Syndrome

    Micro-Vascular Dysfunction After Spinal Cord Injury

    Angiogenesis During Tumor Proliferation and Cell Invasion

    Neuronal-Glial-Endothelial Interactions Regulate Central Nervous System Homeostasis


    Edited by

    Esperanza Meléndez Herrera, profesor e investigador titular A, Departamento de Zoología, Universidad Michoacana de San Nicolas de Hidalgo, México

    Bryan V. Phillips-Farfán, investigador en ciencias médicas C, Instituto Nacional de Pediatria, Coyoacán, México

    Gabriel Gutiérrez Ospina, investigador titular B, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, Coyoacán, México