This book addresses relevant issues that tissue-engineering researchers must consider when planning new strategies, especially in the bone and cartilage field. It describes transcription factors that are essential in bone development, and deals with bone healing.
Table of Contents
Part I: Building Blocks of Osteogenesis 1. Transcription Factors in Bone: Developmental and Pathological Aspect 2. Skeletal Stem Cells 3. Bone Morphogenetic Proteins and Tissue Engineering of Bone 4. Mechanobiology of Bone Part II: Bone Healing 5. Bone Healing and Failure 6. Calcium Phosphate Bioceramics: An Alternative to Autograft and Allograft 7. Mechanical Modulation of Fracture Healing and Implications for Skeletal Tissue Engineering 8. Experimental Animal Models for Tissue-Engineered Bone Regeneration Part III: Tissue Engineering of Bone 9. Delivery of Osteogenic Regulatory Growth Factor 10. Gene Therapy for the Enhancement of Fracture Healing 11. Cell Therapy for the Enhancement of Bone Repair 12. Repair of Osteochondral Lesions 13. Maxillofacial Bone Regeneration Using Tissue Engineering Concepts 14. Clinical Evaluation of BMPs and Bone Marrow Stromal Cells in Orthopedic Surgery Part IV: From the Bench to the Bedside 15. Regulatory Issues: Down to the Bare Bone