Providing a significant cross-fertilization of ideas across several disciplines, Enhancement in Drug Delivery offers a unique comprehensive review of both theoretical and practical aspects of enhancement agents and techniques used for problematic administration routes. It presents an integrated evaluation of absorption enhancers and modes for promoting absorption that is especially valuable to those involved with the development of pharmaceutical, cosmetic, bioengineered, and medical products, as well as graduate students looking to study this intriguing field and those professionals involved with patents and regulatory issues.
Organized by routes of administration, the book is divided into eight major sections: oral, rectal, buccal/sublingual, dermal/transdermal, nasal, vaginal/uterine, ocular, and brain. It offers fundamental as well specialized information including current findings on—
· Surfactant use to accelerate macromolecule input
· Targeted gastrointestinal delivery and enhanced absorption of lipophilic drugs
· Permeation issues in rectal absorption
· Chemical means of enhancement
· Carriers for enhanced delivery to and across the skin
· Methods associated with breaching the skin
· Promoted buccal and sublingual absorption
· Emerging ocular, nasal, vaginal, and uterine delivery systems
· Carriers for overcoming the blood brain barrier
Those investigators primarily involved with one specific route of delivery will be able to learn of helpful concepts and find additional stimulat
Table of Contents
Promoted Gastrointestinal Drug Absorption. Promoted Rectal Absorption. Enhancement of Buccal and Sublingual Absorption. Transdermal Enhanced Delivery. Nasal Absorption Optimization. Drug Absorption from Vagina and Uterus. Systemic Absorption through the Ocular Route. Drug Delivery to the Central Nervous System.
Elka Touitou, Brian W. Barry