Environmental Stress and Cellular Response in Arthropods: 1st Edition (Hardback) book cover

Environmental Stress and Cellular Response in Arthropods

1st Edition

By Andre Korsloot, Cornelis A. M. van Gestel, Nico M. van Straalen

CRC Press

208 pages | 1 Color Illus. | 45 B/W Illus.

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Hardback: 9780415328869
pub: 2004-03-29
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While the subject of environmental stress in animals is broad, the available information is fragmentary and lacks an up-to-date overview and analysis. Environmental Stress and Cellular Response in Arthropods fills these knowledge gaps. Written by three experts from the same institution, the chapters have a consistency not often found in multi-authored or contributed books. The authors describe environmental stress in arthropods, specifically Drosophila and analyze the process in all its aspects, from biochemical mechanisms to effects on the whole organism.

Incorporating new information that has become available in recent years, the authors explore hypotheses about the integrated response these systems often have. They explore topics ranging from disturbance of homeostasis, changes in metabolic processes, damage of cellular structures to acquired tolerance, effects on aging processes, and survival and cell death. By analyzing all these aspects in detail at the molecular, biochemical, and physiological level of the cell, the authors give you a thorough look at the relationship between an organism and its environment at the cellular level.


“… cover the effects of and responses to challenges fro the environment at the cellular level. … Overall, the authors make a great effort to provide a complete introduction for all researchers interested in cellular stress responses. …”

— Jesper G. Sorensen, Genetics & Ecology, University of Aarhus, Denmark, in The Quarterly Review of Biology, Vol. 82, No. 1, March 2007

“…provides those undertaking toxicogenomics studies with a working outline for the identification of common transcriptional responses, as well as unique responses associated with particular exposures. … a valuable contribution to the stress response literature.”

British Toxicology Society Newsletter, Winter 2004, Issue 25

Table of Contents



What is Stress?

Environmental Stressors

Stress Effects Disturbing Cellular Homeostasis

Stress Defense Systems and Their Response to Stress

Scope and Purpose of this Book

Basal signal transduction systems involved in stress response


Two Major Second Messenger Systems: cAMP and Ca 2+

The MAPK Cascade

The stress-protein system


Types, Structures, and Functions of Stress Proteins

Gene Expression, Posttranscriptional, and Translational Regulation of Stress Proteins

The oxidative stress response system


Cellular Response to Reactive Oxygen Species

The Metallothionein System


Properties and Types of Metallothionein

Regulation of Metallothionein

Heavy Metal Stress

The mixed-function oxygenase system


Description of the Mixed-Function Oxygenase System

The Mixed-Function Oxygenase System in Insects

Degradation of Xenobiotics in Insects

The role of cellular response systems in developing tolerance to environmental stress


Thermotolerance in Insect Species

The Effects of Environmental Stress on Aging and Cell Death


Effects of Environmental Stress on Aging

Cell Death by Environmental Stress

The integrated cellular stress defense system


Specific Characteristics of the Individual Systems

Important Stress Effects

Cooperation and Integration of Systems

The Central Hypothesis




Subject Categories

BISAC Subject Codes/Headings:
SCIENCE / Life Sciences / Zoology / Entomology
SCIENCE / Environmental Science