Enzymology of Complex Alpha-Glucans  book cover
1st Edition

Enzymology of Complex Alpha-Glucans

Edited By

Felix Nitschke

  • Available for pre-order. Item will ship after February 15, 2023
ISBN 9780367763053
February 15, 2023 Forthcoming by CRC Press
298 Pages 15 Color & 43 B/W Illustrations

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Book Description

Glycogen and Starch: So Similar, yet so Different. Both carbohydrates are central to the primary metabolism of a large part of the living kingdom. Generally, animals, fungi, and bacteria store glycogen, while plants largely rely on starch. This book provides a broad and current view on both glycogen and starch, in lower and higher organisms. Beside biochemistry, physiology and regulation of glycogen and starch metabolism, the reader can expect an insight into glycogen storage diseases, select methods and relevant techniques. While significant progress has been made in both fields, this volume emphasizes an opportunity of collaboration for researchers working on a major intersection of the living world.

Table of Contents

Morphological and Structural Aspects of a -Glucan Particles from Electron Microscopy Observations

Jean-Luc Putaux

Polarimetric Nonlinear Microscopy of Starch Granules: Visualization of the Structural Order of α-Glucan Chains within a Native Starch Particle

Danielle Tokarz, Richard Cisek and Virginijus Barzda

Analyses of Covalent Modifications in α-Glucans

Felix Nitschke and Peter Schmieder

Storage Polysaccharide Metabolism in Micro-Organisms

Christophe Colleoni

Mammalian Glycogen Metabolism: Enzymology, Regulation, and Animal Models of Dysregulated Glycogen Metabolism

Bartholomew A. Pederson

The Pathologies of a Dysfunctional Glycogen Metabolism

Mitchell A. Sullivan, Berge A. Minassian and Felix Nitschke

Reversible Phosphorylation in Glycogen and Starch

Katherine J. Donohue, Andrea Kuchtova, Craig W. Vander Kooi and Matthew S. Gentry

Starch Granules and their Glucan Components

Eric Bertoft

Regulation of Assimilatory Starch Metabolism by Cellular Carbohydrate Status

Maria Grazia Annunziata and John Edward Lunn

Reserve Starch Metabolism

Yasunori Nakamura

Heteromeric Protein Interactions in Starch Synthesis

Michael J. Emes, Gregory J. MacNeill and Ian J. Tetlow

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Felix Nitschke received his Ph.D. from the University of Potsdam, Germany (2013), under Dr. Martin Steup, an accomplished expert in starch metabolism. Early on Dr. Nitschke’s work focused on particular glycogen storage diseases where pathological insoluble "starch-like" glycogen particles are accumulating, and for instance, drive the progressive childhood-onset epilepsy Lafora disease. After a post-doc under Dr. Berge Minassian at The Hospital for Sick Children, Toronto, Canada, Dr. Nitschke was recruited as Assistant Professor at UT Southwestern Medical Center.