Glycogen and Starch: So Similar, yet so Different. Both carbohydrates are central to the primary metabolism of a large part of the living kingdom. Generally, animals, fungi, and bacteria store glycogen, while plants largely rely on starch. This book provides a broad and current view on both glycogen and starch, in lower and higher organisms. Beside biochemistry, physiology and regulation of glycogen and starch metabolism, the reader can expect an insight into glycogen storage diseases, select methods and relevant techniques. While significant progress has been made in both fields, this volume emphasizes an opportunity of collaboration for researchers working on a major intersection of the living world.
Morphological and Structural Aspects of a -Glucan Particles from Electron Microscopy Observations
Jean-Luc Putaux
Polarimetric Nonlinear Microscopy of Starch Granules: Visualization of the Structural Order of α-Glucan Chains within a Native Starch Particle
Danielle Tokarz, Richard Cisek and Virginijus Barzda
Analyses of Covalent Modifications in α-Glucans
Felix Nitschke and Peter Schmieder
Storage Polysaccharide Metabolism in Micro-Organisms
Christophe Colleoni
Mammalian Glycogen Metabolism: Enzymology, Regulation, and Animal Models of Dysregulated Glycogen Metabolism
Bartholomew A. Pederson
The Pathologies of a Dysfunctional Glycogen Metabolism
Mitchell A. Sullivan, Berge A. Minassian and Felix Nitschke
Reversible Phosphorylation in Glycogen and Starch
Katherine J. Donohue, Andrea Kuchtova, Craig W. Vander Kooi and Matthew S. Gentry
Starch Granules and their Glucan Components
Eric Bertoft
Regulation of Assimilatory Starch Metabolism by Cellular Carbohydrate Status
Maria Grazia Annunziata and John Edward Lunn
Reserve Starch Metabolism
Yasunori Nakamura
Heteromeric Protein Interactions in Starch Synthesis
Michael J. Emes, Gregory J. MacNeill and Ian J. Tetlow
Biography
Felix Nitschke received his Ph.D. from the University of Potsdam, Germany (2013), under Dr. Martin Steup, an accomplished expert in starch metabolism. Early on Dr. Nitschke’s work focused on particular glycogen storage diseases where pathological insoluble "starch-like" glycogen particles are accumulating, and for instance, drive the progressive childhood-onset epilepsy Lafora disease. After a post-doc under Dr. Berge Minassian at The Hospital for Sick Children, Toronto, Canada, Dr. Nitschke was recruited as Assistant Professor at UT Southwestern Medical Center.
