While there are many excellent texts focused on clinical medical imaging, there are few books that approach in vivo imaging technologies from the perspective of a scientist or physician–scientist using, or interested in using, these techniques in research. It is for these individuals that Essentials of In Vivo Biomedical Imaging is written.
Featuring contributions from leading experts in the field, this authoritative reference text helps answer the following often-asked questions: Can imaging address my question? Which technique should I use? How does it work? What information does it provide? What are its strengths and limitations? What applications is it best suited for? How can I analyze the data?
By explaining what each imaging technology can measure, describing major methods and approaches, and giving examples demonstrating the rich repertoire of modern biomedical imaging to address a wide range of morphological, functional, metabolic, and molecular parameters in a safe and noninvasive manner, Essentials of In Vivo Biomedical Imaging helps scientists and physician–scientists choose and utilize the appropriate in vivo imaging technologies and methods for their research.
Table of Contents
Simon R. Cherry, Ramsey D. Badawi, and Jinyi Qi
X-Ray Projection Imaging and Computed Tomography
Kai Yang and John M. Boone
Magnetic Resonance Imaging
Jeff R. Anderson and Joel R. Garbow
K. Kirk Shung
Optical and Optoacoustic Imaging
Adrian Taruttis and Vasilis Ntziachristos
Pat B. Zanzonico
Quantitative Image Analysis
Hsiao-Ming Wu and Wen-Yih I. Tseng
Simon R. Cherry is a distinguished professor in the Departments of Biomedical Engineering and Radiology, as well as director of the Center for Molecular and Genomic Imaging, at the University of California, Davis, USA. He earned a Ph.D in medical physics from the Institute of Cancer Research, London, UK. Dr. Cherry’s research interests include radiotracer imaging, optical imaging, and hybrid multimodality imaging systems, focusing on the development of new technologies, instrumentation, and systems. Dr. Cherry has more than 25 years of experience in the field of biomedical imaging and has authored 200+ publications, including the textbook Physics in Nuclear Medicine. He is a fellow of the Institute for Electrical and Electronic Engineers, the Biomedical Engineering Society, and the Institute of Physics in Engineering and Medicine.
Ramsey D. Badawi is an associate professor in the Departments of Radiology and Biomedical Engineering at the University of California, Davis, USA (UC Davis). He currently serves as chief of the Division of Nuclear Medicine and holds the molecular imaging endowed chair in the Department of Radiology. Dr. Badawi earned a bachelor’s degree in physics and a master’s degree in astronomy from the University of Sussex, UK. He earned a Ph.D in positron emission tomography (PET) physics from the University of London, UK. Prior to joining UC Davis, Dr. Badawi worked at St. Thomas’ Hospital, London, UK; the University of Washington, Seattle, USA; and the Dana Farber Cancer Institute, Boston, Massachusetts, USA. His current research interests include PET and multimodality imaging instrumentation, image processing, and imaging in clinical trials.
Jinyi Qi is a professor in the Department of Biomedical Engineering at the University of California, Davis, USA (UC Davis). He earned a Ph.D in electrical engineering from the University of Southern California, Los Angeles, USA. Prior to joining the faculty of UC Davis, he was a research scientist in the Department of Functional Imaging at the Lawrence Berkeley National Laboratory, California, USA. Dr. Qi is a fellow of the American Institute for Medical and Biological Engineering, a fellow of the Institute for Electrical and Electronic Engineers (IEEE), and an associate editor of IEEE Transactions of Medical Imaging. Dr. Qi’s research interests include statistical image reconstruction, medical image processing, image quality evaluation, and imaging system optimization.
"This is an excellent introductory book, valuable in its recognition of the interdisciplinary biomedical scientist researcher, and notable for its readability and well-balanced coverage. It will be appreciated by scientific researchers finding themselves involved in a project with an unfamiliar imaging technique, or by the more experienced researcher preparing to meet with an imaging specialist. It is also an attractive introductory text for a medical physicist."
—Scope, September 2015
"While material is presented at some depth, using appropriate mathematics, physics, and engineering when necessary for those who really want to dig into a particular imaging technique, it also is a book for the more casual user of imaging. Large fractions of the text are accessible to researchers independent of their specific scientific background, where the emphasis is on explaining what each imaging technology can measure, describing major methods and approaches, and giving examples demonstrating the rich repertoire of modern biomedical imaging to address a wide range of morphological, functional, metabolic, and molecular parameters in a safe and noninvasive manner."
—SirReadaLot.org, October 2015
"The book is well written and attractively produced and I believe it will prove genuinely useful to the target audience and also to a wider range of scientists who make use of imaging for their work or find the topic interesting."
–Contemporary Physics (2016), review by Prof. Peter V. E. McClintock
"This textbook … makes biomedical imaging accessible to researchers from a wide variety of academic disciplines."
—Steven Meikle, Professor of Medical Imaging Physics, The University of Sydney, Australia
"… a very good overview of in vivo biomedical imaging technologies … appropriate for biomedical engineering, electrical engineering, and medical physics students. The inclusion of the chapter on quantitative image analysis methods is timely."
—John D. Hazle, Professor and Chairman, Department of Imaging Physics, and Bernard W. Biedenharn Chair in Cancer Research, University of Texas MD Anderson Cancer Center, Houston, USA
"Terrific book. It is essential reading for anyone using imaging as a research tool."
—Michael F. Insana, Willett Professor of Engineering, Department of Bioengineering, University of Illinois at Urbana-Champaign, USA
"An ideal overview of medical imaging systems for anyone looking for clarity in presentation of the systems and a simple elegance to understanding them. The authors have achieved a balance of getting to the point and yet providing just enough text and illustration to understand it."
—Brian W. Pogue, Professor of Engineering, Physics & Astronomy, and Surgery, Geisel School of Medicine, Dartmouth College, Hanover, New Hampshire, USA
"An excellent book … very comprehensive with ample color figures, which make it easy to read. I strongly recommend this book to students, scientists, and faculty that work in the field of biomedical imaging."
—Weibo Cai, Associate Professor of Radiology and Medical Physics, University of Wisconsin–Madison, USA
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