1st Edition

Exploring Medical Biotechnology- in vivo, in vitro, in silico Biotechnology from Labs to Clinics and Basic to Advanced

Edited By Pratik Talukder, Ritesh Tandon, Uttam Pal Copyright 2024
    316 Pages 59 B/W Illustrations
    by CRC Press

    This book on medical biotechnology offers a wide array of topics and cutting-edge research in the field featuring contributions from multiple authors, each specializing in their respective areas, making it highly valuable to science students and enthusiasts. The book provides comprehensive coverage on a diverse range of topics including sequence analysis, network pharmacology, drug discovery, CRISPR-Cas technology, precision medicine, neuroimaging biomarkers, therapeutics for neurodegenerative diseases, molecular pathogenesis of various diseases, plant-derived antioxidants, genetic approaches for disease diagnosis, cancer progression, immunotherapy, cancer biomarker identification, RNA Interference (RNAi) and nanotechnology in drug discovery and delivery, thus giving a holistic understanding of medical biotechnology.

    Each chapter delves into the latest research and developments in its respective field and offers readers insights into cutting-edge advancements in medical biotechnology. This up-to-date information will be invaluable to science students and enthusiasts who want to stay at the forefront of the field.

    The book adopts an interdisciplinary approach by incorporating elements of biology, genetics, computational techniques, nanotechnology and more, which enables readers to see the interconnectedness of different scientific disciplines and how they contribute to medical biotechnology.

    The book emphasizes practical applications, such as drug discovery, disease treatment, gene editing and targeted drug delivery. This focus on real-world applications is useful to readers interested in applying biotechnological techniques in the medical field. The book also acknowledges the serious challenges faced in the field of medical biotechnology and offers potential solutions to overcome these challenges to foster innovative thinking.

    As a reader, you will gain a comprehensive understanding of various aspects of medical biotechnology, equipping you with knowledge that can contribute to technological breakthroughs, advancements in medicine and the betterment of human life.

    Sequence Analysis to Decipher Protein Functions in Health and Disease

    Animesh Mondal

    Network Pharmacology as a Potential Tool to Unlock the Treasure Trove of Pharmaeuticals in Natural Products

    Pritam Biswas, Uttam Pal

    Drug Discovery Approaches Targeting Dengue Protease

    Rajdip Misra, Shubham Kundu, Anupam Maity, Uttam Pal, N.C. Maiti

    Modern Computational tools for Vaccine Engineering

    Debabrata Ghosh Dastidar, Kamalesh Roy, Disha Bhattacharya, Amlan Das

    Precision Medicine: Scope and Significance

    Susmita Mukherjee, Sonali Paul

    Use of CRISPR-Cas Technology in Medical Biotechnology

    Krishnendu Sarkar

    CRISPR-Cas9: Molecular Scissors in Medical Biotechnology

    Sankha Banerjeea, Arunima Senguptab, Santanu Chakraborty

    In Silico Drug Development: Overview with An Example

    Sonali Paul, Nivedita Chatterjee, Asmeeta Sircar, Shimantika Maikap, Abhilasha Singh, Susmita Mukherjee

    The Role of Neuro-imaging Biomarkers in Early Detection of Dementia and  Alzheimer’s Disease

    Maitrayee Mukherjee

    Therapeutics for Neurodegenerative Diseases

    Shubham Kundu, Anupam Maity,Rajdip Misra,Uttam Pal, N.C. Maiti

    Role of Medical Biotechnology Research in the Field of Neurodegenerative Disease Treatment

    Nilay Nandi, Shashank Shekhar

    The Clinical Manifestation and Molecular Orientation of Huntington Chorea

    Pratik Talukder, Anushka Ghosh, Arpan Banerjee

    The Clinical Manifestation and Molecular Orientation of Leishmaniasis

    Pratik Talukder, Sounak Chanda, Suravi Datta

    Molecular Pathogenesis of Ebola Virus

    Pratik Talukder, Rajarshi Ray, Mainak Sarkar,Anirban Das, Baishakhi Sinha, Arundhuti Mukherjee, Srishti Chakraborty

    Importance of Antioxidants in the Field of Medical Biotechnology

    Tista Basu, Suranjana Sarkar

    In Vitro Genetic Approaches to Identify Disease Gene Mutations

    Pratik Talukder, Anushka Dutta, Suravi Datta

    In Vitro Models for Studying Cancer Progression

    Pratik Talukder, Sounak Chanda, Meghna Mishra, Baishakhi Sinha, Anushka Dutta, Ayan Adhikary

    Immunotherapy: Adding A New Dimension to Cancer Therapy

    Susmita Mukherjee, Shreya Banerjee, Chiranjeeb Dey, Sonali Paul

    Analytical Tools to Identify Cancer Biomarkers from Extracellular Vesicles

    S. Saroj, D. Paul, U. S. Poornima, T. Rakshit

    RNA Interference (RNAi): A Boon to Medical Biotechnology

    Shreya Das, Chandrani Dey, Santanu Chakraborty, Arunima Sengupta

    Nanocarriers for Targeted Drug Delivery

    Rajeswari Tiwari, Sumit Pramanik

    Theranostic Applications of Nanomaterials in Human Health and Disease

    Anupam Maity, Rajdip Misra, Shubham Kundu, Kaushik Bera, Pranga Prava Mandal, Uttam Pal, N.C. Maiti

    Biography

    Dr. Pratik Talukder obtained his PhD in Science from University of Calcutta, India. Currently Dr. Talukder is working as an Associate Professor in the department of Biotechnology, University of Engineering and Management, Kolkata (UEMK). He is a university rank holder in his postgraduate degree. He is the recipient of the prestigious national postdoctoral fellowship of Science and Engineering Research Board (SERB), Department of Science & Technology, Government of India. He is from the background of molecular biology, biophysics, bioinformatics and tissue culture. He has published many research and reviewed articles in several journals of international repute. He has published more than 50 research and review articles in several peer reviewed journals of international repute and book chapters. He is the assistant editor of the journal - ‘Applied Biochemistry and Biotechnology’. He has also received research project grants from the Govt. of India. He is also a member of the European union FRACTION PROJECT for Pedagogy in Higher education,

    Uttam Pal obtained his PhD in Science from Jadavpur University, India. He is a university rank holder in his postgraduate degree from the University of Calcutta and a recipient of INSPIRE Fellowship. Dr. Pal served as a scientist working on translational research at the Technical Research Centre of SN Bose National Centre for Basic Sciences, India. His research interests are computational drug discovery and in silico design and characterization of nano biomaterials for medical applications. He has developed binding specificity and drugability indices within the concept of molecular docking. He is a member of the Royal Society of Chemistry, London and several other scientific societies. He has published many research and review articles and reviewed articles for several journals. Additionally, he currently serves as a guest associate editor for the Frontiers in Chemistry and Applied Biochemistry and Biotechnology journals.

    Dr. Tandon is a Scientist in National Institute of Health (NIH, USA). He was formerly an associate professor of microbiology and immunology at UMMC. He contributes significantly to research, teaching and service. Dr. Tandon is recognized internationally for his research on herpes viruses. His research is supported by several extramural and intramural grants and he serves on AHA as well as NIH grant review study sections. He is a Fellow of the American Heart Association (FAHA). He directs the Graduate Virology Course at UMMC and team teaches three other Microbiology courses. Dr. Tandon also holds a joint assistant professor position in the Department of Biomolecular Sciences at the University of Mississippi. He has published many research and reviewed articles in several journals of international repute.