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Foot and Mouth Disease
Current Perspectives




ISBN 9780849329517
Published August 12, 2004 by CRC Press
600 Pages 64 B/W Illustrations

 
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Book Description

The shock following the recent outbreak of foot-and-mouth disease (FMD) in the UK dispelled the notion that this disease was permanently under control and could be forgotten. FMD proved to be an endemic disease in many countries and continues to pose a major threat to animal health worldwide. The development of more effective and socially acceptable diagnosis and control measures is essential to effectively combat this devastating virus.

Foot and Mouth Disease: Current Perspectives benefits researchers by presenting the latest developments resulting from the upsurge in data concerning this disease. Interdisciplinary in its approach, this book offers the first coherent picture of emerging strategies for diagnosis and control. With contributions from respected FMD researchers worldwide, this volume provides comprehensive coverage of the entire spectrum of FMD issues.

Topics include genome organization, translation and replication of FMD virus RNA, proteinases, virus particles, clinical signs of FMD, and much more. This book delivers essential information for everyone with an interest in FMD, such as virologists, molecular biologists, biotechnologists, veterinarians, and pharmaceutical and biotech researchers.

Table of Contents

Stepping Stones in Foot-and-Mouth Research: A Personal View
F. Brown

Genome Organization, Translation and Replication of Foot-and-Mouth Disease Virus RNA
Graham J. Belsham and Encarnacion Martinez-Salas

Foot-and-Mouth Disease Virus Proteinases
Martin D. Ryan, Michelle L.L. Donnelly, Mike Flint, Vanessa M. Cowton, Garry Luke, Lorraine E. Hughes, Caroline Knox and Pablo de Felipe

Structure of Foot-and-Mouth Disease Virus Particles
Cristina Ferrer-Orta and Ignacio Fita

Clinical Signs of Foot-and-Mouth Disease
Alex Donaldson

Persistence of Foot-and-Mouth Disease Virus
J.S. Salt

Molecular Aspects of Foot-and-Mouth Disease Virus Virulence and Host Range: Role of Host Cell Receptors and Viral Factors
Barry Baxt and Elizabeth Rieder

Immunology of Foot-and-Mouth Disease
Kenneth C. McCullough and Francisco Sobrino

Functional and Structural Aspects of the Interaction of Foot-and-Mouth Disease Virus with Antibodies
Mauricio G. Mateu and Nuria Verdaguer

Quasispecies Dynamics and Evolution of Foot-and-Mouth Disease Virus
Esteban Domingo, Carmen M. Ruiz-Jarabo, Armando Arias, Juan Garcia-Arriaza and Cristina Escarmis

Modern Inactivated Foot-and-Mouth Disease (FMD) Vaccines: Historical Background and Key Elements in Production and Use
S.J. Barteling

Foot-and-Mouth Disease Virus Peptide Vaccines
David J. Rowlands

Mathematical Models of the Epidemiology and Control of Foot-and-Mouth Disease
Mark E.J. Woolhouse

Natural Habitats in which Foot-and-Mouth Disease Viruses are Maintained
Wilna Vosloo and Gavin R. Thomson

Diagnosis and Control of Foot-and-Mouth Disease
R.P. Kitching

Control of Foot-and-Mouth Disease: Role of International Organizations
J. Blancou, Y. Leforban, J.E. Pearson

Overview of Foot-and-Mouth Disease and its Impacts as a Re-Emergent Viral Infection
Brian W.J. Mahy

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Reviews

"The relevance of this overview publication is apparent … . … [Chapters are] well-written … [and] effectively illustrated … . Additionally, the latest information gleamed from the increasing number of publications concerning this disease is offered … . … Virologists, molecular biologists, veterinarians, animal scientists, microbiologists, biotechnologists and prominently pharmaceutical and biotech researchers will find this updated review a significant insight into this increasingly concerning disease … . … A most timely publication that has global importance."
- Vet Human Toxicol, 46 (6), Dec. 2004