Foot and Mouth Disease: Current Perspectives, 1st Edition (Hardback) book cover

Foot and Mouth Disease

Current Perspectives, 1st Edition

Edited by Francisco Sobrino, Esteban Domingo

CRC Press

600 pages | 64 B/W Illus.

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Hardback: 9780849329517
pub: 2004-08-12
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The shock following the recent outbreak of foot-and-mouth disease (FMD) in the UK dispelled the notion that this disease was permanently under control and could be forgotten. FMD proved to be an endemic disease in many countries and continues to pose a major threat to animal health worldwide. The development of more effective and socially acceptable diagnosis and control measures is essential to effectively combat this devastating virus.

Foot and Mouth Disease: Current Perspectives benefits researchers by presenting the latest developments resulting from the upsurge in data concerning this disease. Interdisciplinary in its approach, this book offers the first coherent picture of emerging strategies for diagnosis and control. With contributions from respected FMD researchers worldwide, this volume provides comprehensive coverage of the entire spectrum of FMD issues.

Topics include genome organization, translation and replication of FMD virus RNA, proteinases, virus particles, clinical signs of FMD, and much more. This book delivers essential information for everyone with an interest in FMD, such as virologists, molecular biologists, biotechnologists, veterinarians, and pharmaceutical and biotech researchers.


"The relevance of this overview publication is apparent … . … [Chapters are] well-written … [and] effectively illustrated … . Additionally, the latest information gleamed from the increasing number of publications concerning this disease is offered … . … Virologists, molecular biologists, veterinarians, animal scientists, microbiologists, biotechnologists and prominently pharmaceutical and biotech researchers will find this updated review a significant insight into this increasingly concerning disease … . … A most timely publication that has global importance."

- Vet Human Toxicol, 46 (6), Dec. 2004

Table of Contents

Stepping Stones in Foot-and-Mouth Research: A Personal View

F. Brown

Genome Organization, Translation and Replication of Foot-and-Mouth Disease Virus RNA

Graham J. Belsham and Encarnacion Martinez-Salas

Foot-and-Mouth Disease Virus Proteinases

Martin D. Ryan, Michelle L.L. Donnelly, Mike Flint, Vanessa M. Cowton, Garry Luke, Lorraine E. Hughes, Caroline Knox and Pablo de Felipe

Structure of Foot-and-Mouth Disease Virus Particles

Cristina Ferrer-Orta and Ignacio Fita

Clinical Signs of Foot-and-Mouth Disease

Alex Donaldson

Persistence of Foot-and-Mouth Disease Virus

J.S. Salt

Molecular Aspects of Foot-and-Mouth Disease Virus Virulence and Host Range: Role of Host Cell Receptors and Viral Factors

Barry Baxt and Elizabeth Rieder

Immunology of Foot-and-Mouth Disease

Kenneth C. McCullough and Francisco Sobrino

Functional and Structural Aspects of the Interaction of Foot-and-Mouth Disease Virus with Antibodies

Mauricio G. Mateu and Nuria Verdaguer

Quasispecies Dynamics and Evolution of Foot-and-Mouth Disease Virus

Esteban Domingo, Carmen M. Ruiz-Jarabo, Armando Arias, Juan Garcia-Arriaza and Cristina Escarmis

Modern Inactivated Foot-and-Mouth Disease (FMD) Vaccines: Historical Background and Key Elements in Production and Use

S.J. Barteling

Foot-and-Mouth Disease Virus Peptide Vaccines

David J. Rowlands

Mathematical Models of the Epidemiology and Control of Foot-and-Mouth Disease

Mark E.J. Woolhouse

Natural Habitats in which Foot-and-Mouth Disease Viruses are Maintained

Wilna Vosloo and Gavin R. Thomson

Diagnosis and Control of Foot-and-Mouth Disease

R.P. Kitching

Control of Foot-and-Mouth Disease: Role of International Organizations

J. Blancou, Y. Leforban, J.E. Pearson

Overview of Foot-and-Mouth Disease and its Impacts as a Re-Emergent Viral Infection

Brian W.J. Mahy

Subject Categories

BISAC Subject Codes/Headings:
MEDICAL / Veterinary Medicine / General
MEDICAL / Veterinary Medicine / Food Animal
NATURE / Animals / General
SCIENCE / Life Sciences / Biology / Microbiology
SCIENCE / Life Sciences / General