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1st Edition

Functional Neuroimaging A Clinical Approach

Edited By Andrei I. Holodny Copyright 2008
    ISBN 9780849370564
    348 Pages 170 Color & 190 B/W Illustrations
    Published June 19, 2008 by CRC Press

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    The first text designed specifically with clinical practitioners in mind, Functional Neuroimaging demonstrates the clinical application and utilization of functional neuroradiology for early diagnosis, neurological decision-making, and assessing response to cancer therapy. Edited by the Founding President of American Society of Functional Neuroradiology, this guide expertly describes the incorporation of this technology into clinical practice and showcases high-quality color images depicting the function and mechanisms of the brain.


    • Helps clinicians incorporate functional neuroradiology into their practice
    • Shows new advancements in functional brain imaging to benefit the diagnosis, management, and treatment of patients
    • Depicts current methods for imaging the central nervous system, as well as cutting-edge approaches for the imaging of brain function
    • Contains 320 intricate, full-color figures comprising the anatomy and function of the brain

    Neuroradiologists, radiologists, neurologists, neurosurgeons, and clinical psychologists will find this an essential guide to enhance the quality of their practice.

    BLOOD OXYGEN LEVEL DEPENDANT FUNCTIONAL MRI (BOLD FMRI). A Historical Perspective on Functional Neuroimaging. Physical Principles of Bold fMRI – What Is Important for the Clinician. Preparing the Patient for the fMRI Study. Optimization of Paradigm Selection and Delivery. Methods of Analysis. Fact or Artifact? Language. Vision, Memory and Higher Cortical Function. Cortical Plasticity. Functional Image Guided Neurosurgery. Developmental Disorders. Neurodegenerative Disorders. DIFFUSION IMAGING. Diffusion Imaging and Tensor Physics for the Clinician. Diffusion Weighted Imaging in Stroke. Diffusion Imaging in Brain Tumors and Treatment Response. DTI of Developmental and Pediatric Disorders. DTI of Neurodegenerative Disorders. DTI and Diffusion Tractography in Brain Tumor Patients. PERFUSION IMAGING. Physical Principles. MR Perfusion Imaging of Tumors and Related Conditions. MAGNETOENCEPHALOGRAPHY (MEG). Principles. Brain Tumors. Seizure Disorders. CLINICAL MOLECULAR IMAGING AND EMERGING NEUROIMAGING APPLICATIONS. Pharmaceutical Agents for Molecular Imaging. In Vivo Tracking of Stem Cells in the CNS (MR, Optical). Monitoring Neuroregeneration and Cell Repair (PET, MR, Optical). Other Experimental Therapeutics. Immunoimaging in the Brain (PET Reporter Technology)


    ANDREI I. HOLODNY is Professor of Radiology at the Weill Medical College of Cornell University and Attending Neuroradiologist at Memorial Sloan-Kettering Cancer Center, New York, New York, USA. He is the Chief of the Neuroradiology Section and Director of the Functional MRI Laboratory at Memorial Sloan-Kettering. Dr. Holodny is the Founding President of the American Society of Functional Neuroradiology and past-President of the Eastern Neuroradiological Society. Dr. Holodny’s studies concentrate principally on functional imaging of central nervous system tumors including blood oxygen level dependent functional MRI and diffusion tractography.

    "There are 29 authors and 18 chapters in this 352-page book, and, although a major emphasis is placed on cortical activation (what many primarily think of when functional imaging is mentioned), the latter half of the book is concerned with diffusion imaging and its derivatives, perfusion images and the metrics derived from such studies, and magnetoencephalography."

    "The book is written for the clinical neuroradiologist, and, aside from some scary-looking formulas and mathematics in the perfusion chapter, the book holds true to that promise."

    "In summary, this book is a winner and puts the current state of clinical functional neuroimaging under 1 cover....Functional Neuroimaging is highly recommended to all practicing neuroradiologists and trainees in neuroradiology fellowship programs."

    (American Society of Neuroradiology, 2008)

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