2nd Edition

Fundamentals of Pharmacology
An Applied Approach for Nursing and Health

ISBN 9780131869011
Published July 5, 2007 by Routledge
984 Pages

USD $74.95

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Book Description

Your comprehensive and current introduction to the fascinating field of Pharmacology, applied to Nursing and Health!  Now fully updated in line with changes in clinical practice, new drugs and research developments.

This clear and readable text will guide you through how drugs act within the body coupled with their clinical application.  Sections covering social, legal and professional issues are included alongside the scientific principles of pharmacology.  Drug groups are considered according to their pharmacological effects, their action on physiological processes and the conditions they are used to treat.

Table of Contents



Brief contents


List of figures

List of tables




Section I Pharmacology within the social context

   Chapter 1 An historical perspective

   Chapter 2 Sociocultural aspects


Section II Pharmacology within the professional context

   Chapter 3 Drug administration and the law

   Chapter 4 Ethical issues

   Chapter 5 The roles and responsibilities of nurses

   Chapter 6 The roles and responsibilities of other health-care professionals


Section III Drug administration and professional responsibilities

   Chapter 7 Drug formulations, storage and routes of administration

   Chapter 8 The clinical decision-making process

   Chapter 9 Drug administration strategies and documentation

   Chapter 10 Medication errors

   Chapter 11 Management of common adverse drug reactions


Section IV General aspects of pharmacology

   Chapter 12 Drug nomenclature

   Chapter 13 Pharmacokinetics: absorption and distribution

   Chapter 14 Pharmacokinetics: metabolism and excretion

   Chapter 15 Drug interactions

   Chapter 16 Pharmacodynamics

   Chapter 17 Drug development, evaluation and safety

   Chapter 18 Pharmacogenetics

   Chapter 19 Pharmacokinetic factors that modify drug action

   Chapter 20 Paediatric pharmacology and pharmacology in older people


Section V Toxicology

   Chapter 21 Poisoning and envenomation

   Chapter 22 Management of clinical overdose

   Chapter 23 Contemporary drugs of abuse

   Chapter 24 Drug abuse in sport


Section VI Autonomic pharmacology

   Chapter 25 General aspects of autonomic pharmacology

   Chapter 26 Adrenergic pharmacology

   Chapter 27 Cholinergic pharmacology


Section VII Chemical mediators

   Chapter 28 Introduction to chemical mediators

   Chapter 29 Histamine and antihistamines

   Chapter 30 Prostaglandins and serotonin

   Chapter 31 Nitric oxide and the endothelins


Section VIII Modulation of behaviour, cognition and motor activity

   Chapter 32 General concepts of central nervous system pharmacology

   Chapter 33 Antipsychotic drugs

   Chapter 34 Anxiolytics and hypnotics

   Chapter 35 Antidepressants and mood stabilisers

   Chapter 36 Drugs used in neurodegenerative disorders

   Chapter 37 Antiseizure drugs and muscle relaxants

   Chapter 38 Central nervous system stimulants


Section IX Drugs used to relieve pain and produce anaesthesia

   Chapter 39 Narcotic analgesics

   Chapter 40 Non-steroidal anti-inflammatory, antipyretic and analgesic drugs

   Chapter 41 General anaesthesia

   Chapter 42 Local anaesthesia


Section X Modulation of oxygenation and perfusion

   Chapter 43 Drugs used to lower blood lipids

   Chapter 44 Antihypertensive drugs

   Chapter 45 Drugs used to promote tissue perfusion

   Chapter 46 Anticoagulants, thrombolytics and antiplatelet drugs

   Chapter 47 Diuretics and other renal drugs

   Chapter 48 Drugs used to treat cardiac insufficiency

   Chapter 49 Fluid and potassium imbalances

   Chapter 50 Antianaemic drugs

   Chapter 51 Drugs used to maintain gas exchange

   Chapter 52 Over-the-counter respiratory medicines


Section XI Modulation of gastrointestinal function

   Chapter 53 Upper gastrointestinal tract drugs

   Chapter 54 Lower gastrointestinal tract drugs

   Chapter 55 Nausea and vomiting


Section XII Modulation of body growth, development and metabolism

   Chapter 56 Drugs and the pituitary gland

   Chapter 57 The thyroid and the pancreas

   Chapter 58 The adrenal cortex and the gonads

   Chapter 59 Hyperuricaemia and gout

   Chapter 60 Obesity


Section XIII Nutritional and natural therapies

   Chapter 61 Vitamins

   Chapter 62 Minerals

   Chapter 63 Amino acids

   Chapter 64 Enteral and parenteral nutrition

   Chapter 65 Herbal medicines


Section XIV Modulation of cellular growth and proliferation

   Chapter 66 Introduction to chemotherapy

   Chapter 67 Sulphonamides and trimethoprim

   Chapter 68 Antibacterial drugs

   Chapter 69 Antituberculotic and antileprotic drugs

   Chapter 70 Antiseptics and disinfectants

   Chapter 71 Antiparasitic drugs

   Chapter 72 Antimalarial drugs

   Chapter 73 Antiviral drugs

   Chapter 74 Antifungal drugs

   Chapter 75 Vaccines and immunomodulating drugs

   Chapter 76 Cytotoxic drugs

   Chapter 77 Gene therapies


Section XV Drugs used topically

   Chapter 78 Drugs used in diseases of the skin

   Chapter 79 Drugs and the eye


Appendix A Common prescription terminology

Appendix B Common US generic drugs names

Appendix C SI units

Appendix D Drug calculations

Appendix E Common symbols used in medication charts

Appendix F Common word mix-ups

Appendix G Drug–herb interactions

Appendix H Orphan drugs





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