2nd Edition

Fundamentals of Pharmacology An Applied Approach for Nursing and Health

    984 Pages
    by Routledge

    976 Pages
    by Routledge

    Your comprehensive and current introduction to the fascinating field of Pharmacology, applied to Nursing and Health!  Now fully updated in line with changes in clinical practice, new drugs and research developments.

    This clear and readable text will guide you through how drugs act within the body coupled with their clinical application.  Sections covering social, legal and professional issues are included alongside the scientific principles of pharmacology.  Drug groups are considered according to their pharmacological effects, their action on physiological processes and the conditions they are used to treat.



    Brief contents


    List of figures

    List of tables




    Section I Pharmacology within the social context

       Chapter 1 An historical perspective

       Chapter 2 Sociocultural aspects


    Section II Pharmacology within the professional context

       Chapter 3 Drug administration and the law

       Chapter 4 Ethical issues

       Chapter 5 The roles and responsibilities of nurses

       Chapter 6 The roles and responsibilities of other health-care professionals


    Section III Drug administration and professional responsibilities

       Chapter 7 Drug formulations, storage and routes of administration

       Chapter 8 The clinical decision-making process

       Chapter 9 Drug administration strategies and documentation

       Chapter 10 Medication errors

       Chapter 11 Management of common adverse drug reactions


    Section IV General aspects of pharmacology

       Chapter 12 Drug nomenclature

       Chapter 13 Pharmacokinetics: absorption and distribution

       Chapter 14 Pharmacokinetics: metabolism and excretion

       Chapter 15 Drug interactions

       Chapter 16 Pharmacodynamics

       Chapter 17 Drug development, evaluation and safety

       Chapter 18 Pharmacogenetics

       Chapter 19 Pharmacokinetic factors that modify drug action

       Chapter 20 Paediatric pharmacology and pharmacology in older people


    Section V Toxicology

       Chapter 21 Poisoning and envenomation

       Chapter 22 Management of clinical overdose

       Chapter 23 Contemporary drugs of abuse

       Chapter 24 Drug abuse in sport


    Section VI Autonomic pharmacology

       Chapter 25 General aspects of autonomic pharmacology

       Chapter 26 Adrenergic pharmacology

       Chapter 27 Cholinergic pharmacology


    Section VII Chemical mediators

       Chapter 28 Introduction to chemical mediators

       Chapter 29 Histamine and antihistamines

       Chapter 30 Prostaglandins and serotonin

       Chapter 31 Nitric oxide and the endothelins


    Section VIII Modulation of behaviour, cognition and motor activity

       Chapter 32 General concepts of central nervous system pharmacology

       Chapter 33 Antipsychotic drugs

       Chapter 34 Anxiolytics and hypnotics

       Chapter 35 Antidepressants and mood stabilisers

       Chapter 36 Drugs used in neurodegenerative disorders

       Chapter 37 Antiseizure drugs and muscle relaxants

       Chapter 38 Central nervous system stimulants


    Section IX Drugs used to relieve pain and produce anaesthesia

       Chapter 39 Narcotic analgesics

       Chapter 40 Non-steroidal anti-inflammatory, antipyretic and analgesic drugs

       Chapter 41 General anaesthesia

       Chapter 42 Local anaesthesia


    Section X Modulation of oxygenation and perfusion

       Chapter 43 Drugs used to lower blood lipids

       Chapter 44 Antihypertensive drugs

       Chapter 45 Drugs used to promote tissue perfusion

       Chapter 46 Anticoagulants, thrombolytics and antiplatelet drugs

       Chapter 47 Diuretics and other renal drugs

       Chapter 48 Drugs used to treat cardiac insufficiency

       Chapter 49 Fluid and potassium imbalances

       Chapter 50 Antianaemic drugs

       Chapter 51 Drugs used to maintain gas exchange

       Chapter 52 Over-the-counter respiratory medicines


    Section XI Modulation of gastrointestinal function

       Chapter 53 Upper gastrointestinal tract drugs

       Chapter 54 Lower gastrointestinal tract drugs

       Chapter 55 Nausea and vomiting


    Section XII Modulation of body growth, development and metabolism

       Chapter 56 Drugs and the pituitary gland

       Chapter 57 The thyroid and the pancreas

       Chapter 58 The adrenal cortex and the gonads

       Chapter 59 Hyperuricaemia and gout

       Chapter 60 Obesity


    Section XIII Nutritional and natural therapies

       Chapter 61 Vitamins

       Chapter 62 Minerals

       Chapter 63 Amino acids

       Chapter 64 Enteral and parenteral nutrition

       Chapter 65 Herbal medicines


    Section XIV Modulation of cellular growth and proliferation

       Chapter 66 Introduction to chemotherapy

       Chapter 67 Sulphonamides and trimethoprim

       Chapter 68 Antibacterial drugs

       Chapter 69 Antituberculotic and antileprotic drugs

       Chapter 70 Antiseptics and disinfectants

       Chapter 71 Antiparasitic drugs

       Chapter 72 Antimalarial drugs

       Chapter 73 Antiviral drugs

       Chapter 74 Antifungal drugs

       Chapter 75 Vaccines and immunomodulating drugs

       Chapter 76 Cytotoxic drugs

       Chapter 77 Gene therapies


    Section XV Drugs used topically

       Chapter 78 Drugs used in diseases of the skin

       Chapter 79 Drugs and the eye


    Appendix A Common prescription terminology

    Appendix B Common US generic drugs names

    Appendix C SI units

    Appendix D Drug calculations

    Appendix E Common symbols used in medication charts

    Appendix F Common word mix-ups

    Appendix G Drug–herb interactions

    Appendix H Orphan drugs






    Alan Galbraith, Shane Bullock, Elizabeth Manias, Barry Hunt, Ann Richards