1st Edition
G Protein-Coupled Receptors in Drug Discovery
376 Pages
by
CRC Press
376 Pages
by
CRC Press
376 Pages
by
CRC Press
Also available as eBook on:
The broad range of G protein-coupled receptors (GPCRs) encompasses all areas of modern medicine and have an enormous impact on the process of drug development. Using disease-oriented methods to cover everything from screening to expression and crystallization, G Protein-Coupled Receptors in Drug Discovery describes the physiological roles of GPCRs and their involvement in various human diseases.... Read more
Introduction. G Protein-Coupled Receptors as Targets for Drug Discovery. G Protein-Coupled Receptors in Cardiovascular Diseases. G Protein-Coupled Receptors in Cancer. G Protein-Coupled Receptors in Metabolic Disease. G Protein- Coupled Receptors in CNS Drug Discovery. Recombinant G Protein-Coupled Receptors for Drug Discovery. High Throughput Screening Assays for G Protein-Coupled Receptors. Bioinformatics/ Molecular Modelling of G Protein-Coupled Receptors. Structure and Dynamics of G Protein-Coupled Receptors. Toward Crystallization of G Protein-Coupled Receptors. Novel Solid-State NMR Methods for Structural Studies on G Protein-Coupled Receptors. Structural Genomics Initiatives on G Protein-Coupled Receptors. Dimerization of G Protein-Coupled Receptors. Orphan G Protein-Coupled Receptors.
Biography
Kenneth H. Lundstrom, Mark L. Chiu
