1st Edition

Gastrointestinal Inflammations and Gut Microbiota Pathophysiology, Management, and Emerging Therapies

Edited By Neeraj Mishra, Sumel Ashique, Anoop Kumar Copyright 2025
384 Pages 49 Color & 2 B/W Illustrations
by CRC Press

384 Pages 49 Color & 2 B/W Illustrations
by CRC Press

This book offers a comprehensive and multi-faceted examination of gastrointestinal inflammations, discussing factors that impact gut health. The initial chapters establish a foundational understanding of gastrointestinal inflammations and the critical role of the gut microbiota. The book then delves into the complex pathophysiology and various risk factors associated with these conditions,... Read more

Chapter 1
Introduction to Gastrointestinal Inflammation and Gut Microbiota

Muneeb Ullah, Mishal Safdar, Jin-Wook Yoo, Raees Khan, Abdul Wahab, Khalid Nawaz, and Muhammad Naeem

 

Chapter 2
 Pathophysiology and Risk Factors Associated with Gastrointestinal Inflammation

Sanjesh Kumar, Mansi Singh, Subhajit Mandal, Priyanka Goswami, Sumel Ashique, Mithun Bhowmick, Pratibha Bhowmick, and Ivan Kahwa

 

Chapter 3
Diagnosis, Screening, and Prevention Techniques of Gastrointestinal Inflammations

Hafiza Sehrish Kiani, Adeel Ahmad Khan, Fahad Thabet Alsulami, Yousef Saeed Alqarni, Abdullah Saleh Alruwaili, Ahmed Ramdan M. Alanazy, Abdul Malik, Rameesha Abid, Mithun Bhowmick, and Arshad Farid

 

Chapter 4
Influence of Gut-Brain Axis on Gastrointestinal Health and Benefits

Sindhu Priya E S, Sandhya Vasanth, Rokeya Sultana, Mohammed Gulzar Ahmed, and B.H. Jaswanth Gowda

 

Chapter 5
Interplay Between SCFAs, ROS, SODs, and Gastrointestinal Inflammations             

Aniruddha Sen, Sanjesh Kumar, Pranshul Sethi, Sumel Ashique, Radheshyam Pal, Mithun Bhowmick, Neeraj Mishra, and Anoop Kumar

 

Chapter 6
Role of Probiotics, Prebiotics, and Postbiotics in Management of Gastrointestinal Inflammations

Aniruddha Sen, Krishnendu Adhikary, Pooja S, Murkute, Sumel Ashique , Radheshyam Pal, Pratibha Bhowmick, and Shriyansh Srivastava

 

Chapter 7
Role of Genetic Factor in Gastrointestinal Inflammation

Priyanka Ray, Tamalika Chakraborty, and Debojyoti Adak

 

Chapter 8
Interaction of Antibiotics with Gut Microbiota and its Implications for Treating Gastrointestinal Inflammations

Md Sadique Hussain, Prince Ahad Mir, Nishant Kumar, Adil Farooq Wali, Sumel Ashique, Roohi Mohi-ud-din, and Reyaz Hassan Mir

Chapter 9
Role of the Immune system in Gstrointestinal Inflammation

Tahreen Taj, Venishaa S, Mithun Bhowmick, Pratibha Bhowmick, Sumel Ashique, Neeraj Mishra, and Farzad Taghizadeh-Hesary

 

Chapter 10
Advancements in Dagnostic Tchniques and Tchnology for Gastroenterology

Sunny Rathee, Vishal Pandey, and Sanjay K. Jain

 

Chapter 11
Gut Microbiota Based Strategies for the Management of Gastrointestinal Inflammations

Sowmiya S, Jasmine R, Selvakumar B. N, Deena Priscilla H,and Rameshkumar Santhanam

 

Chapter 12
Nanoparticles-Based Approaches for the Management of Gastrointestinal Inflammations

Vasu Peddinti, Biswajit Rout, Shyam Sudhakar Gomte, Tejas Girish Agnihotri,and Askanchha Jain

 

Chapter 13
Experimental Animal Models and In-Vitro Models for Gastrointestinal Inflammation

Phool Chandra, Zeeshan Ali, Nishat Fatma, and Neetu Sachan

 

Chapter 14

The Neuroinflammation Enigma:  Cracking the Code of the Gut-Brain Connection

Abhimanyu Thakur, Dipanjan Ghosh, Rajesh Sarkar, Sera Averbek, Ashok Iyaswamy, Prabhat Upadhyay, Sarika Gupta, Vikas Kumar,and Amrenda K Ajay

 

Chapter 15
Functional Foods and Nanocarriers for the Management of  Gastrointestinal Inflammations

Amit Anand, Kenganora Mruthunjaya, Santhepete Nanjundiah.Manjula, Neeraj Kumar Fuloria, and Hemanth P.R. Vikram

 

Chapter 16
Polysaccharide-Based Nanoparticles for the Management of Gastrointestinal Inflammations

Jitu Halder, Tushar Kanti Rajwar, Ajit Mishra, Guru Prasanna Sahoo, Biswakanth Kar, Goutam Ghosh, and Goutam Rath

Chapter 17
Lipid Nanocarriers for the Treatment of Gastrointestinal Inflammations

Anas Islam, Ambareen Fatima Ahmed, Asad Ahmad, Usama Ahmad, and Yusuf Asad

 

Chapter 18

Exosomes Mediated Nanocarriers for Gastrointestinal Inflammation Management

Sakshi Soni, Aashi Jain, Priyanshu Nema, Prof. Vandana Soni, and Sushil K. Kashaw

 

Chapter 19
Plant-Based Bio-Actives Encapsulated Nanocarriers for Gastrointestinal Inflammations Management
Subhasundar Maji, Sandipan Dasgupta, Ria Das, and Slim Smaoui

Chapter 20
Future Prospects and Clinical Studies for the Treatment of Gastrointestinal Inflammations
Sanjeeb Kumar Kar, Shubhrajit Mantry, Ashutosh Behera, Laliteshwar Pratap Singh, Brijyog, Deepak Kumar Patra

Biography

Dr. Neeraj Mishra has been serving as a Professor at the Amity Institute of Pharmacy, Gwalior, since July 2019. He brings approximately 20 years of experience in teaching and research. Dr. Mishra has published over 100 papers of international and national significance, focusing on novel drug delivery systems, oral delivery of synbiotics, localized drug delivery, and targeted and controlled drug delivery using nanocarriers and microparticles for treating breast and colon cancer, as well as neurodegenerative disorders. He has also edited more than 15 books and authored 25 book chapters. He is the recipient of the “Distinguished Professor Award” (2019) from DST-NSTMIS, SPAICS, Indore, Madhya Pradesh, and the “Outstanding Scientist Award” (2020) from the 6th International Scientist Awards on Engineering, Science, and Medicine, held in Chennai, India. Further, Dr. Mishra received the “Distinguished Professor Award” in 2021 from the Indian Pharmaceutical Association, MP State Branch, Indore, and the “Best Academician Award” at the Indian Pharmacy Graduate Association’s M.P. State International Conference, held on May 6, 2023, at the DAVV Auditorium, Indore, India.

Dr. Sumel Ashique has been working as an Assistant Professor at Bengal College of Pharmaceutical Sciences & Research, Durgapur 713212, West Bengal, India. He has 4 years of teaching experience. He has achieved 80 publications in International and national accredited reputed journals. He has knowledge in drug delivery, nanotechnology and targeted treatment strategy. He is working as potential reviewer for many well-known publishers (Elsevier, Springer, Dove Press, and Bentham Sc.). He has also five granted patents from IP and Australia, 20 published book chapters in Bentham, Springer, Elsevier, Bentham and Taylor & Francis. Currently is editing 14 books under CRC Press, Elsevier, Taylor and Francis, Wiley, Nova Science and Springer. He has published 80+ papers including research, reviews, column articles, editorials in Scopus, and WOS indexed. He is serving as guest editor in JoVE journal (IF 1.2, Scopus & WOS indexed), Current Probiotics (Bentham Science) & Current Indian Science Journal. He is a potential reviewer for Elsevier, Springer, Taylor & Francis and Wiley journals for expertise in the field of targeted drug delivery, nanotechnology, gut-microbiome and postbiotics. Current he is pursuing his PhD degree from Lovely Professional University, Punjab, India (NAAC A++) in the Pharmaceutical Science department.

Dr. Anoop Kumar is currently serving as an Assistant Professor in the Department of Pharmacology and Clinical Research at Delhi Pharmaceutical Sciences & Research University (DPSRU), New Delhi, India. Previously, he held the position of Assistant Professor in the Department of Pharmacology and Toxicology at the National Institute of Pharmaceutical Education and Research (NIPER), Raebareli. He has also served as an Associate Professor and Officiating Head in the Department of Pharmacology at ISF College of Pharmacy, Moga, Punjab. Additionally, Dr. Kumar has worked as a research scientist in the Medical Affairs and Clinical Research Department at Sun Pharmaceutical Limited, Gurugram, and at the Translational Health Science and Technology Institute (THSTI), Faridabad, India. Dr. Kumar has authored over 80 research and review articles and 15 book chapters in internationally renowned journals. He is also the author of three books. He has received research grants from the Indian government. His research interests include drug repurposing using computational, in vitro, and in vivo techniques, meta-analysis, signal analysis in pharmacovigilance, and pharmacoeconomic studies.