Gene Therapy for Diseases of the Lung: 1st Edition (Hardback) book cover

Gene Therapy for Diseases of the Lung

1st Edition

Edited by Kenneth Brigham

CRC Press

416 pages

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Hardback: 9780824700607
pub: 1997-04-10
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Description

This up-to-the-minute and comprehensive resource lucidly covers gene therapy for lung diseases from existing technologies delivering foreign DNA to the lungs via the airways or circulation to promising new approaches for the further development of safe and efficient gene delivery systems.

Table of Contents

Overview

Human Gene Therapy: The Initial Concepts, W. French Anderson

Discovering Genes That Cause Disease, Francis S. Collins

Delivering Genes to Human Lungs

Adenoviral Vectors for Gene Therapy of Inherited and Acquired Disorders of the Lung, David T. Curiel and Robert I. Garver, Jr.

Adeno-Associated Virus-Based Delivery Systems, Pamela L. Zeitlin

Cellular Responses to Adenovirus Entry, Susanna Chiocca and Matthew Cotton

Catonic Lipid-Based Gene Delivery: An Update, Xiang Gao

Liposome/Viral Hybrid Gene Delivery Systems, Arlene A. Stecenko

Gene Therapy in the Lung: The Next Generation

Manipulating the Intracellular Trafficking of Nucleic Acids, Kathleen E. B. Meyer, Lisa S. Uyechi, and Francis C. Szoka, Jr.

Delivery of Genes Through the Lung Circulation, David M. Rodman and Elizabeth G. Nabel

Targeting Gene Expression to the Lung, Jeffrey A. Whitsett and Stephan W. Glasser

Strategies to Accomplish Targeted Gene Delivery Employing Tropism-Modified Adenoviral Vectors, Joanne T. Douglas and David T. Curiel

Disease-Directed Gene Therapy

Toward Correction of the Genetic Defect in Cystic Fibrosis, Larry G. Johnson and Richard C. Boucher

Correction of the Genetic Defect in Alpha-1 Antitrypsin Deficiency by Somatic Gene Therapy, Randy C. Eisensmith and Savio L. C. Woo

Gene Therapy for Chronic Inflammatory Diseases of the Lungs, Angelo E. Canonico

Gene Therapy for Acute Diseases of the Lungs, Kenneth L. Brigham

Gene Therapy for Lung Cancer, Choon-Taek Lee and David P. Carbone

Epilogue

The Regulatory Process and Gene Therapy, Suzanne Epstein

Some Issues Affecting Progress Toward Human Gene Therapy and Potential Application to the Lung, Theodore Friedmann

About the Series

Lung Biology in Health and Disease

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Subject Categories

BISAC Subject Codes/Headings:
MED079000
MEDICAL / Pulmonary & Thoracic Medicine
MED107000
MEDICAL / Genetics
SCI049000
SCIENCE / Life Sciences / Biology / Molecular Biology