Gene Therapy for Neurological Disorders: 1st Edition (Hardback) book cover

Gene Therapy for Neurological Disorders

1st Edition

Edited by Pedro R. Lowenstein, Maria G. Castro

CRC Press

384 pages | 26 Color Illus. | 47 B/W Illus.

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Hardback: 9780824728472
pub: 2006-05-01
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eBook (VitalSource) : 9780429136245
pub: 2016-04-19
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Coedited by internationally recognized leaders in gene therapy research, this guide supplies the most recent advances, studies, and expert opinion on gene therapy for neurological disorders. Spanning conditions such as Parkinsons's and Alzheimer's disease, multiple sclerosis, brain tumors, stroke, epilepsy, and brain and spinal cord trauma, this reference presents the basic science and applications of recombinant gene products, immune and stem cell-mediated therapeutic strategies, and brain tumor gene therapy.

Table of Contents

Immune Responses to Viral Vectors: Implications for Neurological Gene Therapy. Gene Transfer to the Nerve System Using HSV-1-Derived Amplicon Vectors. Adeno Associated Viral Vectors for the Nervous System. Heat Shock Proteins for Neurological Gene Therapy. iBAC Technologies for Neurological Disease. Targeted Gene Modification of the Nervous System. Astrocytes as Targets for Neurological Gene Therapy. Targeting Non-Viral Gene Transfer Vectors: What We Learn From Viruses & Other Pathogens. Gene Therapy Applications for Parkinson's Disease. HSV-Mediated Gene Transfer in the Treatment of Chronic Pain. Immunotherapeutic Approaches for Alzheimer's Disease. Gene Therapy of Multiple Sclerosis and in CNS Autoimmune Mouse Models. Novel Gene Therapeutic Approaches to Brain Cancer. Vaccines and Beneficial Immunity in Glioma Patients. Replicating Viruses for Brain Tumor Treatment. Adenovirus-mediated HSV-tk Gene Therapy for Malignant Glioma: Clinical Experience

Subject Categories

BISAC Subject Codes/Headings:
MEDICAL / General
MEDICAL / Neurology
MEDICAL / Genetics