1st Edition
General Analytical Chemistry Separation and Spectral Methods
This book provides key information about the instrumental analytical methods which are the most used in quantitative analysis. A theoretical knowledge of each method is discussed. The methods are illustrated with several examples covering a wide range such as pharmacy, biochemical, environmental and agrochemicals analysis. It is structured into three parts: the first one focuses on separation methods, the second covers the spectroscopic ones and the third part develops the thermal and the radiochemical methods.
SEPARATION METHODS: INTRODUCTION TO THE METHODS OF SEPARATION. Separation of a Mixture of Distinct Phases. Resolution of a Solid Phase in its Constituents. Separation by Rupture of Phase. Partition Coefficient—Thermodynamic Basis. Dialysis—Osmosis and Reverse Osmosis. Generalities Upon the Liquid-Liquid Extractions. One Stage of Liquid-Liquid Extraction: Batch Extraction. Crosscurrent Extraction or Repetitive Batchwise Extraction by an Immiscible Solvent. Countercurrent Extraction. Countercurrent Separation or Discontinuous Liquid-Liquid Countercurrent Separation. Solid Phase Extraction and Microextraction. Distillation. Chromatographic Methods: An Overview. Fundamental Theoretical Aspects of Elution Chromatography. Practical Consequences of the Plates Theory: Qualitative and Quantitative Aspects of the Chromatography. Basic Principles of Chromatographic Modes. Instrumental Chromatographic Methods. Electro-Migration Techniques . SPECTRAL METHODS: INTRODUCTION TO THE SPECTRAL METHODS. Instrumentation in Spectrophotometry. Ultraviolet-visible Spectroscopy I: Generalities. Ultraviolet-visible Spectroscopy II: Applications Analytiques. Molecular Luminescence Spectrometry: Fluorescence, Phosphorescence and Chemiluminescence. Turbidimetry and Nephelometry. Nuclear Magnetic Resonance Spectroscopy with Continuum Waves: General Principles. N.M.R. Spectra Fundamentals: Characteristics and Analytical Applications. Fourier Transforms and Fourier Transforms N.M.R. Electron Spin Resonance (E.S.R.) and Electron Paramagnetic Resonance (E.P.R.). Infrared Spectroscopy I: Fundamentals of Infrared Spectra. Infrared Spectroscopy II: Apparatus, Qualitative and Quantitative Analysis MID, Infrared Reflection and Near-Infrared Spectrometries. Raman Spectroscopy. Polarimetry. Rotatory Dispersion: Circular Dichroism. Introduction to the Atomic Absorption and Emission Spectroscopies. Atomic Absorption Spectrometry. Atomic Emission Spectrometry. Analysis by X-Rays. Radiochemical Methods of Analysis. VARIOUS METHODS: INTRODUCTION: DEFINITIONS AND CLASSIFICATION OF THE THERMAL METHODS OF ANALYSIS. Thermogravimetry. Thermal Differential Analysis and Calorimetric Differential Analysis. Thermometric Titration. Mass Spectrometry. Some Kinds of Mass Spectrometry and Some Mass Spectrometers and Components. Applications of Mass Spectrometry. Criteria of Purity. Appendices.
Biography
Gwenola Burgot, Pharmacist, PhD, formerly Professor in Analytical Chemistry, Faculty of Pharmaceutical and Biological Sciences of University of Rennes 1. Scientific adviser for the collection database "Techniques de l’Ingénieur". Her research interests and publications involve the determination by continuous adiabatic titration calorimetric method of physicochemical equilibrium, water/n-octanol kinetic and thermodynamic parameters of transfer of drugs and the optimization of analytical methods for quantitative analysis of drugs in pure form or formulations.
Jean-Louis Burgot, Pharmacist, PhD in organic chemistry and PhD in analytical chemistry – thermometric titrimetry, formerly Professor in Analytical Chemistry, Faculty of Pharmaceutical and Biological Sciences of University of Rennes 1. His research interests and publications involve the synthesis and study of the physico-chemical properties of 1,2-Dithiole-3-thiones and derivatives, and the determination of thermodynamic and kinetic constants of pharmacologically active compounds. He has published seven books in French and English.
