562 Pages 77 Color & 5 B/W Illustrations
by CRC Press

562 Pages 77 Color & 5 B/W Illustrations
by CRC Press

Genetic polymorphisms are important determinants of phenotypic variations and may modulate the risk to or even cause various diseases including genetic disorders and multifactorial diseases. Genetic polymorphisms also serve as important genetic, population and evolutionary markers that allow the study of genetic and evolutionary aspects of individuals, populations and organisms and aid in tracing... Read more

Chapter 1 - Genetic Polymorphisms - Classification, Structure, Detection and Function

Mujeeb Zafar Banday

Aga Syed Sameer

Saniya Nissar

Chapter 2 - Clinical relevance of Pharmacogenomics a road to personalized medicine

Nusrath Yasmeen

Shobana John

Vikram Kumar

Moudi M Alasmari

Chapter 3 - Diabetes and Role of SNPs in diabetes susceptibility

Johra Khan

Sayequa Dandoti

Chapter 4 - Genetic polymorphism associated with innate immune response to Malaria

Amre Nasr

Amir Abushouk

Chapter 5 - Xenobiotic Metabolic Enzyme Polymorphisms and cancer susceptibility

Saniya Nissar
Aga Syed Sameer
Mujeeb Zafar Banday
Fouzia Rashid

Chapter 6 - Genetic Polymorphisms in Matrix Metallo-Proteinase (MMP) Genes and Cancer

Mujeeb Zafar Banday

Saniya Nissar

Aga Syed Sameer

Ehtishamul Haq

Sabhiya Majid

Chapter 7 - Vitamin D receptor polymorphisms and diseases

Aga Syed Sameer

Mujeeb Zafar Banday

Saniya Nissar

Mansour AlQurashi

Abdullah Awadh

Alqassem Hakami

Israa A Malli

Chapter 8 - Genetic Polymorphism in Fatty Acid Metabolism Genes and Cancer Susceptibility

Mosin S Khan

Sunia Faiz

Iqra Farooq

Suhail S Lone

Sabhiya Majid

Waseem Qureshi

Chapter 9 - Single nucleotide polymorphisms (SNPs) and Parkinson's disease

Saniya Nissar

Aga Syed Sameer

Mujeeb Zafar Banday

Sabhiya Majid

Chapter 10 - Genetic Polymorphisms, role in drug metabolism and effect on Clinical Pharmacy

Muneeb U Rehman

Shagufta Sheikh

Sanjeev Rana

Hilal A Wani

Aarif Ali

Qazi Danish

Sabhiya Majid

Nisar A Naikoo

Nouroz Sehar

Amjad Faihan Binlebdah

Azher Arafah

Chapter 11 - Role of genetic polymorphisms om Chronic Inflammatory disease

Saniya Nissar

Aga Syed Sameer

Mujeeb Zafar Banday

Roohi Rasool 

Chapter 12 - Single nucleotide polymorphism related computational-resources part I: Databases

Nadiem Nazir Bhat

Showkat Ahmad Dar

Manmeet Kaur

Pallawi Kumari

Chapter 13 - Single nucleotide polymorphism related computational-resources part II: Algorithms

Nadiem Nazir Bhat

Showkat Ahmad Dar

Manmeet Kaur

Pallawi Kumari

Chapter 14 - Role of single nucleotide polymorphisms (SNPs) in common migraine

Aga Syed Sameer
Saniya Nissar
Mujeeb Zafar Banday
Kulsum Akhtar
Razaz Felemban
Moudi M Alasmari
Faheem Hyder Potto
Sheikh A Saeed

Chapter 15 - The Role of Vitamin D Single Nuclear Polymorphisms in Cancer Susceptibility

Abdullah A. Awadh

Chapter 16 - Genetic polymorphisms in fatty acid metabolism genes and cancer susceptibility

Racha Kerek 

Chapter 17 - Toll-Like Receptor (TLR) Polymorphisms in Prostate Cancer

Payam BEHZADI

Chapter 18 - Role of Single Nucleotide Polymorphism of Cytochrome P450 Genes in Cancer Susceptibility

Faheem Hyder Pottoo

Sachin Kuma

Rajiv Kumar Tonk

Chapter 19 - Role of Single Nucleotide Polymorphisms of Inflammatory molecules in susceptibility to Cardiovascular diseases (CVDs)

Saniya Nissar

Vishal Kumar Deb

Ahmad Rabbani

Sabhiya Majid

Amir Abushouk

Johra Khan

Bader H Khawaji

Ruqaya Aziz

Mujeeb Zafar Banday

Yasmeen Nusrath 

Chapter 20 - Role of Single Nucleotide Polymorphisms of Inflammatory molecules in susceptibility to Cardiovascular diseases (CVDs)

Syed Mudassar

Kulsum Akhtar

Ishrat Parveiz Bhat

Chapter 21 - Cytokine polymorphism and their role in modulating cancer risk

Mosin S Khan

Iqra Farooq

Sunia Faiz

Suhail S Lone

Sabhiya Majid

Waseem Qureshi 

Chapter 22 - Gastric Cancer and genetic polymorphism in modulating the susceptibility

Muneeb U Rehman

Shagufta Sheikh

Sanjeev Rana

Hilal A Wani

Aarif Ali

Nouroz Sehar

Sabhiya Majid

Nisar A Naikoo

Bashayr M. Alsuwayni

Azher Arafah

Chapter 23 - Cytokine Gene Polymorphisms & their Role in Autoimmune Diseases

Syed Mudassar

Kulsum Akhtar

Ishrat Parveiz Bhat

Aga Syed Sameer

Syed Douhath Yousuf

Chapter 24 - Genomic disturbances associated with penile cancer and novel therapies

Herney Andrés García-Perdomo

María Juliana Chaves-Medina

Chapter 25 - Role of Genetic Polymorphisms in Gastric Cancer Susceptibility

Syed Mudassar

Syed Douhath Yousuf

Biography

Dr. Syed Sameer Aga is currently working as an Assistant Professor of Biochemistry in the Department of Basic Medical Sciences, College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Jeddah, Saudi Arabia. He is also serving as the Chairman of the Quality Assurance Unit in College of Medicine, KSAU-HS. Dr. Syed is a life-time member of many societies related to genetics, molecular biology and medical education like the Royal Society of Biology, Biochemical Society, Association of Clinical Biochemists of India, Society of Indian Academy of Medical Genetics, Middle East Molecular Biology Sources, Asian Council of Science Editors, and Saudi Society of Medical Education, etc. He is also serving as the Associate Editor in five Journals, Frontiers in Oncology – Molecular Biosciences section, BioMed Research International, Education Research International, World Journal of Biological Chemistry and Current Drug Metabolism. He also serves as a full time reviewer for various journals including European Journal of Cancer Prevention (Lippincott Williams & Wilkins), PLOS One & PLOS Genetics (Public Library of Science), World Journal of Gastroenterology (Baishideng Publishing), BMC Medical Genetics (BMC-Springer), Gene & Meta Gene (Elsevier Publishing), Bioscience Reports (Portland Press), Journal of Clinical Laboratory Analysis (John Wiley & Sons) and Tumor Biology (Sage Journals) etc. His research interests are focused on cancer biology and he has published more than ninety research and review articles in high repute journals with an h-index of 22 and authored ten books.

Dr. Mujeeb Zafar Banday is presently working as a Senior Researcher and Lecturer in the Department of Biochemistry, Govt. Medical College, Srinagar. Dr. Banday has completed his Ph.D., M.Phil. and M.Sc. in Biochemistry from the University of Kashmir, J&K, India. He is serving as the review editor and associate reviewer for the journal, Frontiers in Oncology - Cancer Epidemiology and Prevention (Frontiers Group) and full time reviewer for various journals including Gene (Elsevier Publishing), Bioscience Reports (Portland Press), BioMed Research International (Hindawi Publishing) and Toxicology and Environmental Health Sciences Review (Springer Nature). He has authored more than twenty research and review articles and three books.

Dr. Saniya Nissar is presently working as a Senior Researcher and Lecturer in the Department of Biochemistry, Govt. Medical College, Srinagar. She has completed her PhD, MPhil, and MSc in clinical biochemistry from the University of Kashmir, J&K, India. She works as free-lance scientific content writer with many scientific magazines. She has published more than thirty research and review articles and authored four books.

This book will be useful to researchers interested in one of the diseases described and those who are new to studying the relationship between a particular disease and inherited variation...[and] is a welcome addition to the currently available literature."

- Mark F. Sanders, PhD (UC Davis College of Biological Sciences)