Genetics of Complex Disease (Paperback) book cover

Genetics of Complex Disease

By Peter Donaldson, Ann Daly, Luca Ermini, Debra Bevitt

© 2015 – Garland Science

450 pages | 141 Color Illus.

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Paperback: 9780815344919
pub: 2015-08-25
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pub: 2015-08-01
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Description

Genetics of Complex Disease examines how the identification of genetic variations that increase or reduce the risk of common, genetically complex, diseases can be used to improve our understanding of the pathology of many common diseases; enable better patient management and care; and help with differential diagnosis. It starts with the questions of "what", "why" and "how," and continues with more specific topics such as HLA and immunogenetics, pharmacogenetics, cancer, and diabetes. It finishes with a discussion of ethical issues, and looks to future developments. Genetics of Complex Disease is designed for advanced undergraduate and graduate students in the biomedical sciences and medicine.

Table of Contents

1. Genetic Diversity

2. Defining Complex Disease

3. How to Investigate Complex Disease Genetics

4. Why Investigate Complex Disease Genetics?

5. Statistical Considerations for the Planning and Analysis of Genetic Studies in Complex Disease.

6. The MHC

7. Genetics of Infectious Disease

8. Pharmacogenetics

9. Cancer as a Complex Disease: Genetic Factors Affecting Cancer Susceptibility and Cancer Treatment

10. Genetic Studies on Susceptibility to Diabetes

11. Ethical, Social and Personal Consequences

12. Sequencing Technology and the Future of Complex Disease Genetics

Subject Categories

BISAC Subject Codes/Headings:
MED022000
MEDICAL / Diseases
MED028000
MEDICAL / Epidemiology
MED107000
MEDICAL / Genetics
SCI029000
SCIENCE / Life Sciences / Genetics & Genomics