Green Coffee Bean Extract in Human Health  book cover
1st Edition

Green Coffee Bean Extract in Human Health

ISBN 9781032097763
Published June 30, 2021 by CRC Press
256 Pages 48 B/W Illustrations

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Book Description

The role of green coffee bean (GCB) in human health is of emerging interest to the nutraceutical field, especially given its role in improving metabolic syndrome, including weight management, hypertension, diabetes, and neuroprotection. GCB extract contains a novel antioxidant known as chlorogenic acid (also caffeoylquinic acid), which has been shown to positively affect blood pressure, brain health, diabetes, and weight management. This book provides information on the diverse health benefits of green coffee bean extract, molecular mechanisms and signaling pathways, safety of GCB, dosage, and recommended usage. It focuses on the chemistry, biochemistry, pharmacology, and safety of GCB extract.

GCB extract has brought a remarkable revolution in the nutraceutical marketplace. However, some controversies have been demonstrated recently. This book presents the state-of-the-art research studies from eminent scientists around the world on the potential and diversified health benefits of GCB extracts, with particular emphasis placed on the importance to standardize the appropriate extraction technology, quality control and assurance, and broad spectrum safety studies and human clinical studies to substantiate the regulatory claims and position the product in the marketplace.

Table of Contents

Green Coffee Bean Extract and Chlorogenic Acids: Chemistry and Novel Antioxidant Benefits
Rajesh K. Kesharwani, Prabhakar Singh, and Raj Kumar Keservani

Chlorogenic Acids in Green Coffee Bean Extract Are a Key Ingredient in Food with Health and Function Claims
Hiroyoshi Moriyama, Orie Yoshinari, and Debasis Bagchi

Chlorogenic Acids from Green Coffee Beans: Standard Quality and Extraction Methods
Natalia Pandjaitan

Occurrence in Plants and In Vitro, Animal and Human Metabolism of Chlorogenic Acids
Maurice J. Arnaud

Mechanism of the Inhibition by Chlorogenic Acids against Postprandial Increase in Blood Glucose Level
Yusaku Narita and Kuniyo Inouye

Beneficial Effects of Green Coffee Bean Extract and Coffee Polyphenols on Metabolic Syndrome
Ichiro Tokimitsu

Antiobesity Profile of Green Coffee Extract
Hiroshi Shimoda

Antihypertension Effects of Green Coffee Bean Extract and Chlorogenic Acids
Ichiro Tokimitsu and Atsushi Suzuki

Therapeutic Potential of Green Coffee Bean in Nonalcoholic Fatty Liver Disease
Rama P. Nair, Debasis Bagchi, Anand Swaroop, and Sreejayan Nair

Caffeic Acid and Its Biological Effects on Brain Function
Myra O. Villareal, Yuki Sato, and Hiroko Isoda

Coffee and Cognition: Extending Our Understanding beyond Caffeine
Karen Nolidin, Christina Kure, Andrew Scholey, and Con Stough

Nontargeted Metabolomics Reveal Changes in Chlorogenic Acids in Ripening Coffea arabica Green Beans
Koichi Nakahara

Effect of Green Coffee Bean Extract on Nrf2/ARE Pathway
Mirza Sarwar Baig and Raj Kumar Keservani

Metabolomics Study of Green Coffee Beans
Anh Hong Phan, Takuya Miyakawa, and Masaru Tanokura

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Debasis Bagchi, PhD, is an Adjunct Professor at the University of Houston College of Pharmacy, Houston, Texas, USA

Hiroyoshi Moriyama, PhD, is a Researcher at the Faculty of Pharma-Science, Laboratory of Drug and Gene Delivery Research, Teikyo University, Tokyo, Japan