1st Edition

Guide to Genital HPV Diseases and Prevention

Edited By William Bonnez Copyright 2009
    152 Pages
    by CRC Press

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    Custom-designed for clinicians on the frontline of treatment and prevention of the human papillomavirus (HPV), this stand-alone handbook provides the scientific background needed to understand and administer the new HPV vaccines. Written by some of the discoverers of these vaccines, this accessible text explores the biology and epidemiology of HPV, its diagnosis, screening, prevention, and treatment, and the types of diseases linked to the virus.

    The Guide to Genital HPV Diseases and Prevention:

    • aids clinicians in addressing patient questions and concerns
    • discusses the basic virology and pathogenesis of HPV
    • explores the relationship between HPV and cancer, especially cancer of the cervix
    • covers the various treatment methods, including both chemical and physical methods
    • details prevention strategies, such as condoms and microbicides, and vaccines (Gardasil, Cervarix, Silgard, and those in development)
    • is an essential reference for an array of clinicians, including family practice physicians, internal medicine specialists, pediatricians, dermatologists, gynecologists, and oncologists

    HPV Disease Burden
    HPV Transmission
    Epidemiology of HPV Infection
    Natural History of Cervical HPV Infection
    Natural History of Cervical HPV Infection in HIV-Positive Women
    Multiple Genotype Infections
    HPV and Cancer—The Causal Link
    HPV and Cervical Cancer—The Causal Model

    External Anogenital Warts
    Other Diseases of the Anogenital Tract
    Diseases of the Head and Neck Area and Other Sites

    The Treatment Modalities
    Approach to Treatment

    Nucleic Acid Detection Methods

    Pathophysiology of the Cervix
    Screening Techniques
    Cervical Cancer Screening Recommendations and Triage
    Indications for Cervical HPV DNA Testing
    Screening in Special Situations
    Screening for Anal Cancer
    New Screening Markers

    Environmental Prevention
    Condoms and Microbicides


    WILLIAM BONNEZ is Associate Professor of Medicine, University of Rochester; Attending Physician, Strong Memorial Hospital; and Attending Physician, Highland Hospital, Rochester, New York, USA. Dr. Bonnez received his M.D. from the Université de Bordeaux II (now called Université Victor Segalen Bordeaux II), Bordeaux, France. As one of the discoverers of the groundbreaking HPV vaccines, his contributions to the field of infectious disease are truly immeasurable. Dr. Bonnez is a member and fellow of several professional societies, including the American College of Physicians, the Infectious Disease Society of America, and the American Society for Virology. In addition, he has received several notable awards throughout his career, such as the Annual Davey Memorial Award for Outstanding Contribution to Cancer Research and the Wilmot’s Inspiration Award (both from the University of Rochester), Distinguished Inventor of the Year 2006 from the Rochester Intellectual Property Law Association, and the Health Care Achievement Award from the Rochester Business Journal. Dr. Bonnez has been an honored guest lecturer and presenter at various international, national, and regional meetings and symposiums on infectious and sexually transmitted diseases, and he frequently contributes to numerous journal publications by serving on editorial and review boards. Such publications include The Open Virology Journal, Antiviral Therapy, and The Journal of Infectious Diseases.