This book discusses the topic of the HLA antigen system. Chapters discuss topics such as; animal studies, the possible mechanisms of HLA and disease associations, statistical and genetic considerations, the clinical use of HLA typing, as well as the current status of HLA and disease associations.
1. Introduction to the HLA antigen system 2. Animal studies as the basis of the relationship of disease susceptibility and immune responsiveness with histocompatibility, Ir, and Ia Antigens 3. Possible mechanisms of HLA and disease associations: sex prevalence 4. Statistical and genetic considerations 5. The clinical use of HLA typing 6. HLA-disease association in the perspective of ABO disease associations 7. Current status of HLA and disease associations 8. Concluding remarks