Handbook of Corynebacterium glutamicum: 1st Edition (Hardback) book cover

Handbook of Corynebacterium glutamicum

1st Edition

Edited by Lothar Eggeling, Michael Bott

CRC Press

632 pages | 121 B/W Illus.

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Hardback: 9780849318214
pub: 2005-03-30
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One of the most important organisms in biotechnology, Corynebacterium glutamicum is currently used to produce 2 million tons of amino acids per year for a rapidly expanding market. Until now, research and information have been scattered among individual papers which are often difficult to locate in a timely manner.

As the first complete compilation of major findings, Handbook of Corynebacterium glutamicum is a comprehensive source of scientific and technical information required for the understanding and manipulation of C. glutamicum. The book summarizes the current knowledge in the field ofC. glutamicum research from its discovery in 1957 through the most recent studies at the genomic and systemic level, and provides a basis for future work. Written by experts from industry and academia, chapters cover all major aspects of C. glutamicum, including physiology, biochemistry, genetics, and industrial applications.

Just as C. glutamicum has proven its profitability in industry and research, this book will demonstrate its value to the scientists striving to understand and develop even more efficient producer strains of this promising microorganism.

Table of Contents

Part I: History

A Short History of the Birth of the Amino Acid Industry in Japan, S. Kinoshita

Part II: Taxonomy

Corynebacterium Taxonomy, W. Liebl

Part III: Genome, Plasmids and Gene Expression

The Genomes of Amino Acid-producing Corynebacteria, J. Kalinowski

Native Plasmids of Amino Acid-producing Corynebacteria, A. Tauch

Regulation of Gene Expression, M. Pátek

Proteomics, S. Schaffer and A. Burkovski

Part IV: Transport

The Cell Envelope of Corynebacteria, M. Daffé

Genomic Analyses of Transporter Proteins in Corynebacterium glutamicum and Corynebacterium efficiens, B. Winnen, J. Felce, and M. H. Saier, Jr.

Export of Amino Acids and Other Solutes, L. Eggeling

Part V: Physiology and Regulation

Central Metabolism: Sugar Uptake and Conversion, A. Yokota and N.D. Lindley

Central Metabolism: Tricarboxylic Acid Cycle and Anaplerotic Reactions, B. Eikmanns

Metabolic Flux Analysis in Corynebacterium glutamicum, C. Wittmann and A.A. De Graaf

Respiratory Energy Metabolism, M. Bott and A. Niebisch

Nitrogen Metabolism and Its Regulation, A. Burkovski

Sulfur Metabolism and Regulation, H.-S. Lee

Phosphorus Metabolism, V.F. Wendisch and M. Bott

Vitamin Synthesis: Carotenoids, Biotin, and Pantothenate, G. Sandmann and H. Yukawa

Osmoregulation, S. Morbach and R. Krämer

Part VI: Synthesis and Production

L-Glutamate Production, E. Kimura

L-Lysine Production, R. Kelle, T. Hermann, and B. Bathe

L-Tryptophan Production, M. Ikeda

Synthesis of L-Threonine and Branched Chain Amino Acids, L.B. Willis, P. A. Lessard, and A. J. Sinskey

Part VII: Experiments


Subject Categories

BISAC Subject Codes/Headings:
MEDICAL / Biotechnology
SCIENCE / Life Sciences / Biology / Microbiology
SCIENCE / Life Sciences / Biology / Molecular Biology